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Reliability of RTVue, Visante, and slit-lamp adapted ultrasonic pachymetry for central corneal thickness measurement

 Jin Pyo Hong  ;  Sang Min Nam  ;  Tae-Im Kim  ;  Kyoung Yul Seo  ;  Sang Yeop Lee  ;  Alessandro Meduri  ;  Eung Kweon Kim 
 YONSEI MEDICAL JOURNAL, Vol.53(3) : 634-641, 2012 
Journal Title
Issue Date
Adult ; Cornea/anatomy & histology* ; Cornea/diagnostic imaging ; Cornea/pathology ; Corneal Topography ; Female ; Humans ; Male ; Reproducibility of Results ; Tomography, Optical Coherence/methods* ; Ultrasonography
Optical coherence tomography ; ultrasonic pachymetry ; reliability ; central corneal thickness
PURPOSE: To evaluate reliability of Fourier-domain optical coherence tomography (OCT) (RTVue), time-domain OCT (Visante), and slit-lamp adapted ultrasonic pachymetry (SL-US) in the measurement of central corneal thickness (CCT). MATERIALS AND METHODS: Thirty healthy volunteers visited our clinic 3 times and fifty eyes were measured by one physician. RTVue and Visante were randomly performed, and then SL-US, in which the ultrasound probe was inserted into the Goldmann tonometry mount, was done. During the second visit, each measurement was repeated 3 times. Measurements on the second visit were averaged, and agreement among the instruments was investigated with Bland-Altman plots. RESULTS: RTVue showed smaller repeatability coefficient than Visante and SL-US (4.7, 8.3, and 7.7 μm, respectively). Intersession reproducibility of RTVue and Visante was worse than their repeatability. CCT of RTVue was estimated to be maximally different by 11.8 μm from CCT of Visante and 8.8 μm from CCT of SL-US. The repeatability coefficient of SL-US was 7.7 μm and its reproducibility was similar to the repeatability. CONCLUSION: CCT measured by RTVue showed good reliability and generally agreed with Visante and SL-US. SL-US was as reliable as triple touching conventional US even with a single touch on the cornea.
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1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Eung Kweon(김응권) ORCID logo https://orcid.org/0000-0002-1453-8042
Kim, Tae Im(김태임) ORCID logo https://orcid.org/0000-0001-6414-3842
Seo, Kyuong Yul(서경률) ORCID logo https://orcid.org/0000-0002-9855-1980
Lee, Sang Yeop(이상엽) ORCID logo https://orcid.org/0000-0002-3834-7953
Hong, Jin Pyo(홍진표)
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