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How to manage thyroid nodules with two consecutive non-diagnostic results on ultrasonography-guided fine-needle aspiration

Authors
 Hee Jung Moon  ;  Jin Young Kwak  ;  Yoon Seong Choi  ;  Eun-Kyung Kim 
Citation
 World Journal of Surgery, Vol.36(3) : 586-592, 2012 
Journal Title
 World Journal of Surgery 
ISSN
 0364-2313 
Issue Date
2012
Abstract
BACKGROUND: The aim of this study was to investigate the factors for considering surgery on thyroid nodules that had non-diagnostic results on two consecutive cytology examinations. METHODS: A total of 104 thyroid nodules with two consecutive non-diagnostic cytology examinations in 104 patients were investigated. Nodules with one or more suspicious ultrasonography (US) features of marked hypoechogenicity, a not well defined margin, microcalcifications, or a taller-than-wide shape were assessed as sonographically suspicious. Those without any suspicious features were assessed as sonographically benign. The clinicopathologic characteristics of patients and US features of the nodules were compared according to malignancy and benignity. The odds ratio for predicting malignancy was calculated. RESULTS: Altogether, 12 nodules were malignant, and 92 were benign. Age, sex, nodule size, and solidness were not associated with malignancy (P = 0.73, 0.92, 0.48, and 0.73, respectively). The malignancy rate of sonographically suspicious nodules was 25.7%, higher than the 4.3% of sonographically benign nodules (P = 0.002). The odds ratio of sonographically suspicious nodules for predicting malignancy was 16.01 (95% confidence interval 2.36-108.54, P = 0.005). CONCLUSIONS: Based on sonographic features, surgery can be performed selectively on nodules with two consecutive non-diagnostic cytology results.
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/92034
DOI
10.1007/s00268-011-1397-8
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실)
Yonsei Authors
곽진영(Kwak, Jin Young) ; 김은경(Kim, Eun-Kyung) ; 문희정(Moon, Hee Jung) ; 최윤성(Choi, Yoon Seong)
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Full Text
http://link.springer.com/article/10.1007%2Fs00268-011-1397-8
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