77 222

Cited 10 times in

Gelatin-layered and multi-sized porous β-tricalcium phosphate for tissue engineering scaffold

 Sung-Min Kim  ;  Soon-Aei Yi  ;  Seong-Ho Choi  ;  Kwang-Mahn Kim  ;  Yong-Keun Lee 
 Nanoscale Research Letters, Vol.7(1) : 78-78, 2012 
Journal Title
 Nanoscale Research Letters 
Issue Date
The multi-sized porous β-tricalcium phosphate scaffolds were fabricated by freeze drying followed by slurry coating using a multi-sized porous sponge as a template. Then, gelatin was dip coated on the multi-sized porous β-tricalcium phosphate scaffolds under vacuum. The mechanical and biological properties of the fabricated scaffolds were evaluated and compared to the uniformly sized porous scaffolds and scaffolds that were not coated by gelatin. The compressive strength was tested by a universal testing machine, and the cell viability and differentiation behavior were measured using a cell counting kit and alkaline phosphatase activity using the MC3T3-E1 cells. In comparison, the gelatin-coated multi-sized porous β-tricalcium phosphate scaffold showed enhanced compressive strength. After 14 days, the multi-sized pores were shown to affect cell differentiation, and gelatin coatings were shown to affect the cell viability and differentiation. The results of this study demonstrated that the multi-sized porous β-tricalcium phosphate scaffold coated by gelatin enhanced the mechanical and biological strengths.
Files in This Item:
T201200698.pdf Download
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Dental Biomaterials and Bioengineering (치과생체재료공학교실) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Periodontics (치주과학교실) > 1. Journal Papers
Yonsei Authors
김광만(Kim, Kwang Mahn)
김성민(Kim, Sung Min)
이순애(Yi, Soon Aei)
이용근(Lee, Yong Keun)
최성호(Choi, Seong Ho) ORCID logo https://orcid.org/0000-0001-6704-6124
RIS (EndNote)
XLS (Excel)
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.