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Uterine artery embolization for symptomatic fibroids with high signal intensity on T2-weighted MR imaging.

 Suyon Chang  ;  Man-Deuk Kim  ;  Myungsu Lee  ;  Mu Sook Lee  ;  Sung Il Park  ;  Jong Yun Won  ;  Do Yun Lee  ;  Kwang Hun Lee 
 KOREAN JOURNAL OF RADIOLOGY, Vol.13(5) : 618-624, 2012 
Journal Title
Issue Date
Adult ; Case-Control Studies ; Contrast Media ; Female ; Humans ; Leiomyoma/therapy* ; Magnetic Resonance Imaging, Interventional/methods* ; Meglumine ; Middle Aged ; Organometallic Compounds ; Retrospective Studies ; Surveys and Questionnaires ; Treatment Outcome ; Uterine Artery Embolization/methods* ; Uterine Neoplasms/therapy*
Fibroid uterus ; Magnetic resonance imaging ; Radiology, Interventional ; Uterine artery embolization
OBJECTIVE: To evaluate the effectiveness of uterine artery embolization (UAE) for treating symptomatic fibroids with high signal intensity (SI) on magnetic resonance (MR) T2-weighted imaging (T2WI). MATERIALS AND METHODS: A total of 537 cases, consisting of 14 patients with high SI fibroids on T2WI (T2 high group), were retrospectively included and compared with 28 randomly selected patients with low SI fibroids on T2WI (control group). High SI of a predominant fibroid on T2WI was defined as having the same or higher SI than the myometrium. Patient ages ranged from 28 to 52 years (mean, 38.1 years). All patients underwent MRI before and after UAE. Predominant fibroid and uterine volumes were calculated with MR images. Symptom status in terms of menorrhagia and dysmenorrhea was scored on a scale of 0-10, with 0 being no symptoms and 10 being the baseline, or initial symptoms. RESULTS: Of the patients in the T2 high group, 13 out of 14 (92.9%) patients demonstrated complete necrosis of the predominant fibroids. The mean volume reduction rates of the predominant fibroids in the T2 high group was 61.7% at three months after UAE, which was significantly higher than the volume reduction rates of 42.1% noted in the control group (p < 0.05). Changes in symptom scores for menorrhagia and dysmenorrhea after UAE (baseline score minus follow-up score) were 4.9 and 7.5 in T2 high group and they were 5.0 and 7.7 in control group, suggesting a significant resolution of symptoms (p < 0.01) in both groups but no significant difference between the two groups. CONCLUSION: UAE is effective for uttering fibroids showing high SI on T2WI. The mean volume reduction rate of the predominant fibroids three months after UAE was greater in the T2 high group than in the control group.
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1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Man Deuk(김만득) ORCID logo https://orcid.org/0000-0002-3575-5847
Park, Sung Il(박성일)
Won, Jong Yun(원종윤) ORCID logo https://orcid.org/0000-0002-8237-5628
Lee, Kwang Hun(이광훈)
Lee, Do Yun(이도연)
Lee, Myung Su(이명수)
Lee, Mu Sook(이무숙)
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