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Cumulative radiation exposure during follow-up after curative surgery for gastric cancer.
DC Field | Value | Language |
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dc.contributor.author | 김기황 | - |
dc.contributor.author | 김명진 | - |
dc.contributor.author | 김영진 | - |
dc.contributor.author | 김주희 | - |
dc.contributor.author | 유제성 | - |
dc.contributor.author | 이여진 | - |
dc.contributor.author | 이혜정 | - |
dc.contributor.author | 임준석 | - |
dc.contributor.author | 정용은 | - |
dc.date.accessioned | 2014-12-19T17:24:05Z | - |
dc.date.available | 2014-12-19T17:24:05Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 1229-6929 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/91338 | - |
dc.description.abstract | OBJECTIVE: To quantify the cumulative effective dose (cED) of radiation due to repeated CT and PET/CT examinations after curative resection of gastric cancer and to assess the lifetime attributable risk (LAR) estimates based on Biological Effects of Ionizing Radiation VII models. SUBJECTS AND METHODS: Patients who underwent a curative resection for gastric cancer between January 2006 and December 2006 and were followed-up until May 2010 were included in this study. The cED was calculated by using the dose-length product values and conversion factors for quantitative risk assessment of radiation exposure. cED and LAR were compared between early and advanced gastric cancer patients and among American Joint Committee on Cancer TNM stage groups (stage I, II, and III). The nonparametric Mann-Whitney U and Kruskal-Wallis tests, followed by a post-hoc analysis with Bonferroni adjustment, were employed as part of the statistical analysis. RESULTS: The overall median cED was 57.8 mSv (interquartile range [IQR], 43.9-74.7). The cED was significantly higher in the advanced (median, 67.0; IQR, 49.1-102.3) than in the early gastric cancer group (median, 52.3; IQR, 41.5-67.9) (p < 0.001), and increased as the TNM stage increased. For radiation exposure, 62% of all patients received an estimated cED of over 50 mSv, while 11% of patients received over 100 mSv. The median LAR of cancer incidence was 0.28% (IQR, 0.20-0.40) and there were significant differences between the early gastric cancer and advanced gastric cancer group (p < 0.001) as well as among the three TNM stage groups (p = 0.015). The LAR of cancer incidence exceeded 1% in 2.4% of the patients. CONCLUSION: The cED increases proportionally along with tumor stage and, even in early gastric cancer or stage I patients, cED is much higher than that found among the general population. Considering the very good prognosis of early gastric cancer after curative surgery, the cED should be considered when designing a postoperative follow-up CT protocol. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | KOREAN JOURNAL OF RADIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Follow-Up Studies | - |
dc.subject.MESH | Gastrectomy | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Multimodal Imaging* | - |
dc.subject.MESH | Neoplasm Staging | - |
dc.subject.MESH | Positron-Emission Tomography* | - |
dc.subject.MESH | Radiation Dosage* | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Risk Assessment | - |
dc.subject.MESH | Statistics, Nonparametric | - |
dc.subject.MESH | Stomach Neoplasms/diagnostic imaging* | - |
dc.subject.MESH | Stomach Neoplasms/pathology | - |
dc.subject.MESH | Stomach Neoplasms/surgery | - |
dc.subject.MESH | Tomography, X-Ray Computed* | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Cumulative radiation exposure during follow-up after curative surgery for gastric cancer. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Emergency Medicine (응급의학) | - |
dc.contributor.googleauthor | Yeo Jin Lee | - |
dc.contributor.googleauthor | Yong Eun Chung | - |
dc.contributor.googleauthor | Joon Seok Lim | - |
dc.contributor.googleauthor | Joo Hee Kim | - |
dc.contributor.googleauthor | Young Jin Kim | - |
dc.contributor.googleauthor | Hye-Jeong Lee | - |
dc.contributor.googleauthor | Je Sung You | - |
dc.contributor.googleauthor | Myeong-Jin Kim | - |
dc.contributor.googleauthor | Ki Whang Kim | - |
dc.identifier.doi | 22438681 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00345 | - |
dc.contributor.localId | A00426 | - |
dc.contributor.localId | A02507 | - |
dc.contributor.localId | A02951 | - |
dc.contributor.localId | A03408 | - |
dc.contributor.localId | A03662 | - |
dc.contributor.localId | A00727 | - |
dc.contributor.localId | A03320 | - |
dc.contributor.localId | A00951 | - |
dc.relation.journalcode | J02884 | - |
dc.identifier.eissn | 2005-8330 | - |
dc.identifier.pmid | 22438681 | - |
dc.subject.keyword | Computed tomography | - |
dc.subject.keyword | Effective dose | - |
dc.subject.keyword | Follow-up | - |
dc.subject.keyword | Gastric cancer | - |
dc.subject.keyword | Lifetime attributable risk | - |
dc.subject.keyword | Radiation exposure | - |
dc.contributor.alternativeName | Kim, Ki Whang | - |
dc.contributor.alternativeName | Kim, Myeong Jin | - |
dc.contributor.alternativeName | Kim, Young Jin | - |
dc.contributor.alternativeName | Kim, Joo Hee | - |
dc.contributor.alternativeName | You, Je Sung | - |
dc.contributor.alternativeName | Lee, Yeo Jin | - |
dc.contributor.alternativeName | Lee, Hye Jeong | - |
dc.contributor.alternativeName | Lim, Joon Seok | - |
dc.contributor.alternativeName | Chung, Yong Eun | - |
dc.contributor.affiliatedAuthor | Kim, Ki Whang | - |
dc.contributor.affiliatedAuthor | Kim, Myeong Jin | - |
dc.contributor.affiliatedAuthor | You, Je Sung | - |
dc.contributor.affiliatedAuthor | Lee, Yeo Jin | - |
dc.contributor.affiliatedAuthor | Lim, Joon Seok | - |
dc.contributor.affiliatedAuthor | Chung, Yong Eun | - |
dc.contributor.affiliatedAuthor | Kim, Young Jin | - |
dc.contributor.affiliatedAuthor | Lee, Hye Jeong | - |
dc.contributor.affiliatedAuthor | Kim, Joo Hee | - |
dc.citation.volume | 13 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 144 | - |
dc.citation.endPage | 151 | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL OF RADIOLOGY, Vol.13(2) : 144-151, 2012 | - |
dc.identifier.rimsid | 30117 | - |
dc.type.rims | ART | - |
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