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Cumulative radiation exposure during follow-up after curative surgery for gastric cancer.

DC FieldValueLanguage
dc.contributor.author김기황-
dc.contributor.author김명진-
dc.contributor.author김영진-
dc.contributor.author김주희-
dc.contributor.author유제성-
dc.contributor.author이여진-
dc.contributor.author이혜정-
dc.contributor.author임준석-
dc.contributor.author정용은-
dc.date.accessioned2014-12-19T17:24:05Z-
dc.date.available2014-12-19T17:24:05Z-
dc.date.issued2012-
dc.identifier.issn1229-6929-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/91338-
dc.description.abstractOBJECTIVE: To quantify the cumulative effective dose (cED) of radiation due to repeated CT and PET/CT examinations after curative resection of gastric cancer and to assess the lifetime attributable risk (LAR) estimates based on Biological Effects of Ionizing Radiation VII models. SUBJECTS AND METHODS: Patients who underwent a curative resection for gastric cancer between January 2006 and December 2006 and were followed-up until May 2010 were included in this study. The cED was calculated by using the dose-length product values and conversion factors for quantitative risk assessment of radiation exposure. cED and LAR were compared between early and advanced gastric cancer patients and among American Joint Committee on Cancer TNM stage groups (stage I, II, and III). The nonparametric Mann-Whitney U and Kruskal-Wallis tests, followed by a post-hoc analysis with Bonferroni adjustment, were employed as part of the statistical analysis. RESULTS: The overall median cED was 57.8 mSv (interquartile range [IQR], 43.9-74.7). The cED was significantly higher in the advanced (median, 67.0; IQR, 49.1-102.3) than in the early gastric cancer group (median, 52.3; IQR, 41.5-67.9) (p < 0.001), and increased as the TNM stage increased. For radiation exposure, 62% of all patients received an estimated cED of over 50 mSv, while 11% of patients received over 100 mSv. The median LAR of cancer incidence was 0.28% (IQR, 0.20-0.40) and there were significant differences between the early gastric cancer and advanced gastric cancer group (p < 0.001) as well as among the three TNM stage groups (p = 0.015). The LAR of cancer incidence exceeded 1% in 2.4% of the patients. CONCLUSION: The cED increases proportionally along with tumor stage and, even in early gastric cancer or stage I patients, cED is much higher than that found among the general population. Considering the very good prognosis of early gastric cancer after curative surgery, the cED should be considered when designing a postoperative follow-up CT protocol.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfKOREAN JOURNAL OF RADIOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAged, 80 and over-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHGastrectomy-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMultimodal Imaging*-
dc.subject.MESHNeoplasm Staging-
dc.subject.MESHPositron-Emission Tomography*-
dc.subject.MESHRadiation Dosage*-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Assessment-
dc.subject.MESHStatistics, Nonparametric-
dc.subject.MESHStomach Neoplasms/diagnostic imaging*-
dc.subject.MESHStomach Neoplasms/pathology-
dc.subject.MESHStomach Neoplasms/surgery-
dc.subject.MESHTomography, X-Ray Computed*-
dc.subject.MESHTreatment Outcome-
dc.titleCumulative radiation exposure during follow-up after curative surgery for gastric cancer.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Emergency Medicine (응급의학)-
dc.contributor.googleauthorYeo Jin Lee-
dc.contributor.googleauthorYong Eun Chung-
dc.contributor.googleauthorJoon Seok Lim-
dc.contributor.googleauthorJoo Hee Kim-
dc.contributor.googleauthorYoung Jin Kim-
dc.contributor.googleauthorHye-Jeong Lee-
dc.contributor.googleauthorJe Sung You-
dc.contributor.googleauthorMyeong-Jin Kim-
dc.contributor.googleauthorKi Whang Kim-
dc.identifier.doi22438681-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00345-
dc.contributor.localIdA00426-
dc.contributor.localIdA02507-
dc.contributor.localIdA02951-
dc.contributor.localIdA03408-
dc.contributor.localIdA03662-
dc.contributor.localIdA00727-
dc.contributor.localIdA03320-
dc.contributor.localIdA00951-
dc.relation.journalcodeJ02884-
dc.identifier.eissn2005-8330-
dc.identifier.pmid22438681-
dc.subject.keywordComputed tomography-
dc.subject.keywordEffective dose-
dc.subject.keywordFollow-up-
dc.subject.keywordGastric cancer-
dc.subject.keywordLifetime attributable risk-
dc.subject.keywordRadiation exposure-
dc.contributor.alternativeNameKim, Ki Whang-
dc.contributor.alternativeNameKim, Myeong Jin-
dc.contributor.alternativeNameKim, Young Jin-
dc.contributor.alternativeNameKim, Joo Hee-
dc.contributor.alternativeNameYou, Je Sung-
dc.contributor.alternativeNameLee, Yeo Jin-
dc.contributor.alternativeNameLee, Hye Jeong-
dc.contributor.alternativeNameLim, Joon Seok-
dc.contributor.alternativeNameChung, Yong Eun-
dc.contributor.affiliatedAuthorKim, Ki Whang-
dc.contributor.affiliatedAuthorKim, Myeong Jin-
dc.contributor.affiliatedAuthorYou, Je Sung-
dc.contributor.affiliatedAuthorLee, Yeo Jin-
dc.contributor.affiliatedAuthorLim, Joon Seok-
dc.contributor.affiliatedAuthorChung, Yong Eun-
dc.contributor.affiliatedAuthorKim, Young Jin-
dc.contributor.affiliatedAuthorLee, Hye Jeong-
dc.contributor.affiliatedAuthorKim, Joo Hee-
dc.citation.volume13-
dc.citation.number2-
dc.citation.startPage144-
dc.citation.endPage151-
dc.identifier.bibliographicCitationKOREAN JOURNAL OF RADIOLOGY, Vol.13(2) : 144-151, 2012-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Emergency Medicine (응급의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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