Cited 34 times in

The effect of visceral fat mass on pancreatic fistula after pancreaticoduodenectomy

Authors
 Chang Min Park  ;  Joon Seong Park  ;  Eun Suk Cho  ;  Jae Keun Kim  ;  Jeong Sik Yu  ;  Dong Sup Yoon 
Citation
 JOURNAL OF INVESTIGATIVE SURGERY, Vol.25(3) : 169-173, 2012 
Journal Title
JOURNAL OF INVESTIGATIVE SURGERY
ISSN
 0894-1939 
Issue Date
2012
MeSH
Aged ; Body Mass Index ; Female ; Humans ; Intra-Abdominal Fat/pathology* ; Male ; Middle Aged ; Multivariate Analysis ; Pancreatic Diseases/complications ; Pancreatic Diseases/pathology ; Pancreatic Diseases/surgery ; Pancreatic Fistula/etiology* ; Pancreaticoduodenectomy/adverse effects* ; Postoperative Complications/etiology* ; Risk Factors ; Subcutaneous Fat/pathology
Keywords
pancreaticoduodenectomy ; pancreatic fistula ; visceral fat area ; obesity
Abstract
BACKGROUND: Obesity is associated with perioperative complications and has been considered a risk factor for surgical outcomes of patients undergoing abdominal surgery. The aim of this study is to evaluate the impact of the amount of visceral fat on postoperative morbidity of patients who underwent pancreaticoduodenectomy (PD).

METHODS: We reviewed 181 patients who underwent surgery for periampullary lesions at the Department of Surgery, Gangnam Severance Hospital, Yonsei University Health System between January 2003 and June 2010. The visceral fat area (VFA) and subcutaneous fat area were calculated by computed tomography software.

RESULTS: The mean body mass index (BMI) was 23.4 kg/m(2) (±3.1 kg/m(2)), and the mean VFA was 94.4 cm(2) (±49.5 cm(2)). The mean intraoperative blood loss, and the incidence of clinically relevant pancreatic fistula (grade B/C) and clinically relevant delayed gastric emptying (grade B/C) were significantly higher in the high-VFA group (≥100 cm(2)). In univariate analysis, the incidence of clinically relevant pancreatic fistula (grade B/C) was significantly higher in the high-BMI group (≥25 kg/m(2)), the high-VFA group(≥100 cm(2)), the large intraoperative blood loss and transfusion group, and in patients with pathology of nonpancreatic origin (ampulla, bile duct, or duodenum). In multivariate analysis, the high-VFA group (≥100 cm(2)) and patients with pathology of nonpancreatic origin were identified as independent factors for clinically relevant pancreatic fistula.

CONCLUSION: VFA is a better indicator for the development of pancreatic fistula after PD than BMI. High VFA (≥100 cm(2)) is a risk factor for developing a pancreatic fistula after PD.
Full Text
http://informahealthcare.com/doi/abs/10.3109/08941939.2011.616255
DOI
10.3109/08941939.2011.616255
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Jae Keun(김재근)
Park, Joon Seong(박준성) ORCID logo https://orcid.org/0000-0001-8048-9990
Park, Chang Min(박창민)
Yoon, Dong Sup(윤동섭) ORCID logo https://orcid.org/0000-0001-6444-9606
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/90872
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links