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Osteoconductivity of porous polyethylene in human skull

 Tark, Woo Hyun  ;  Yoon, In Sik  ;  Rah, Dong Kyun  ;  Park, Beyoung Yun  ;  Kim, Yong Oock 
 Journal of Craniofacial Surgery, Vol.23(1) : 78-80, 2012 
Journal Title
 Journal of Craniofacial Surgery 
Issue Date
PURPOSE: Recently, biomaterials have been generally used in reconstruction of a bony defect or augmentation of the facial skeleton. Medpor implants in vivo in animal models showed both soft tissue and bony ingrowth into its pores and have been widely accepted to have an osteoconduction activity. However, in an in vivo study in humans, there was no definite evidence of bony ingrowth into the pores of Medpor. This study examined the osteoconductivity of Medpor in human vivo. METHODS: We gained a total of 24 Medpor blocks when removing a distraction device in 11 patients with craniosynostosis. The Medpor blocks were used for secure placement of the distraction device. The blocks were taken out after distraction and consolidation periods. The surface of Medpor in contact with the bone was histologically examined to confirm the osteogenic activity. RESULTS: There was no evidence of osteoconduction in all 24 specimens. The mean total duration of implantation was 2.5 months. CONCLUSIONS: In human vivo, implantation of a porous polyethylene implant is thought to have no osteogenetic effect through osteoconductive activity even in young children.
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1. College of Medicine (의과대학) > Dept. of Plastic and Reconstructive Surgery (성형외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Yong Oock(김용욱) ORCID logo https://orcid.org/0000-0002-3756-4809
Rah, Dong Kyun(나동균)
Park, Beyoung Yun(박병윤)
Yun, In Sik(윤인식) ORCID logo https://orcid.org/0000-0003-1103-7047
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