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Dual-source coronary CT angiography in patients with high heart rates using a prospectively ECG-triggered axial mode at end-systole.

Authors
 Hee Yeong Kim  ;  Ji Won Lee  ;  Yoo Jin Hong  ;  Hye-Jeong Lee  ;  Jin Hur  ;  Ji Eun Nam  ;  Byoung Wook Choi  ;  Young Jin Kim 
Citation
 International Journal of Cardiovascular Imaging, Vol.28(suppl 2) : 101-107, 2012 
Journal Title
 International Journal of Cardiovascular Imaging 
ISSN
 1569-5794 
Issue Date
2012
MeSH
Aged ; Cardiac-Gated Imaging Techniques/methods* ; Cardiac-Gated Imaging Techniques/standards ; Chi-Square Distribution ; Coronary Angiography/methods* ; Coronary Angiography/standards ; Coronary Artery Disease/diagnostic imaging* ; Coronary Artery Disease/physiopathology ; Electrocardiography* ; Feasibility Studies ; Female ; Heart Rate* ; Humans ; Male ; Middle Aged ; Predictive Value of Tests ; Radiation Dosage ; Reference Standards ; Sensitivity and Specificity ; Systole ; Tomography, Spiral Computed*/standards
Keywords
Computed tomography ; Cardiac-gated imaging techniques ; Coronary angiography ; Heart rate ; Radiation dosage
Abstract
To determine the feasibility of dual-source coronary CT angiography (CTA) using a prospectively electrocardiogram (ECG)-triggered axial mode to target end-systole in patients with high heart rates (HR) as compared with the retrospective mode. One hundred fifty consecutive patients with regular HR > 75 bpm who underwent coronary CTA were enrolled; 75 patients underwent prospectively ECG-triggered coronary CTA targeting only end-systole (Prospective Axial Group) and 75 patients underwent retrospectively ECG-gated coronary CTA (Retrospective Helical Group). The image quality of multiple coronary artery segments was evaluated and radiation doses were recorded. The diagnostic performance of coronary CTA was compared to the reference standard of invasive coronary angiography in 52 patients (35 %) (28 patients in Prospective Axial Group and 24 patients in Retrospective Helical Group). Image quality was not significantly different between the 2 groups (P = 0.784). In subgroup analysis, segment-based sensitivity, specificity, and positive and negative predictive values of coronary CTA were 98, 96, 88 and 99 %, respectively, in the Prospective Axial Group and were 97, 95, 82, and 99 %, respectively, in the Retrospective Helical Group. Mean radiation dose was significantly lower for the Prospective Axial Group than for the Retrospective Helical Group (2.9 ± 1.4 vs. 7.4 ± 3.3 mSv; P < 0.0001). Dual source coronary CTA with a prospective ECG-triggered axial mode targeting end-systole is feasible in patients with regular high HRs for evaluation of coronary artery disease. It provides comparable image quality and diagnostic value with substantially lower radiation exposure as compared to the retrospective ECG-gated helical technique.
Full Text
http://link.springer.com/article/10.1007%2Fs10554-012-0142-1
DOI
23099512
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Young Jin(김영진) ORCID logo https://orcid.org/0000-0002-6235-6550
Kim, Hee Yeong(김희영)
Nam, Ji Eun(남지은)
Lee, Ji Won(이지원)
Lee, Hye Jeong(이혜정) ORCID logo https://orcid.org/0000-0003-4349-9174
Choi, Byoung Wook(최병욱) ORCID logo https://orcid.org/0000-0002-8873-5444
Hur, Jin(허진) ORCID logo https://orcid.org/0000-0002-8651-6571
Hong, Yoo Jin(홍유진) ORCID logo https://orcid.org/0000-0002-7276-0944
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/90459
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