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토끼 두개골 모델에서 탈회동종골, 탈회우골, 및 합성 Hydroxyapatite의 골재생 비교연구

 Ming-Lan Zhang  ;  Otgonbayar Unursaikhan  ;  양혜주  ;  이중석  ;  정의원  ;  김창성  ;  최성호 
 Biomaterials Research (생체재료학회지), Vol.16(4) : 140-146, 2012 
Journal Title
 Biomaterials Research (생체재료학회지) 
Issue Date
Allograft ; Xenograft ; Hydroxyapatite ; Bone regeneration ; Calvaria
The purpose of this study was to compare bone regenerative effects of allograft, xenograft, and alloplast bone substitutes in rabbit calvarial defects. 14 male New Zealand rabbits were used. Four defects with a diameter of 8 mm were created on each animal. Demineralized bone matrix (DBM) gel, bovine bone (BB) and hydroxyapatite (HA) were used as the three test groups, while the control group was left unfilled. The animals were sacrificed after 2 and 8 weeks of healing. All experimental groups at 8 weeks showed statistically significant differences in new bone formation compared 2 weeks. Residual biomaterials in sites received DBM gel decreased compared to the sites received BB and HA. Within the limits of this study, there were no significant differences in bone regeneration between the sites received DBM gel, BB, and HA.
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2. College of Dentistry (치과대학) > Dept. of Periodontics (치주과학교실) > 1. Journal Papers
5. Research Institutes (연구소) > Institute for Periodontal Tissue Regeneration (치주조직재생연구소) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Dental Biomaterials and Bioengineering (치과생체재료공학교실) > 1. Journal Papers
Yonsei Authors
Kim, Chang Sung(김창성) ORCID logo https://orcid.org/0000-0003-3902-1071
Unursaikhan, Otgonbayar(어운희)
Lee, Jung Seok(이중석) ORCID logo https://orcid.org/0000-0003-1276-5978
Zhang, Ming Lan(장명란)
Jung, Ui Won(정의원) ORCID logo https://orcid.org/0000-0001-6371-4172
Choi, Seong Ho(최성호) ORCID logo https://orcid.org/0000-0001-6704-6124
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