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Hepatocellular carcinoma: clinical and radiological findings in patients with chronic B viral hepatitis and chronic C viral hepatitis

Authors
 Kyung Eun Kim  ;  Mi-Suk Park  ;  Stuart Bentley-Hibbert  ;  Song-Ee Baek  ;  Young Chul Kim  ;  Myeong-Jin Kim  ;  Ki Whang Kim  ;  Yong H. Auh 
Citation
 ABDOMINAL IMAGING, Vol.37(4) : 591-594, 2012 
Journal Title
 ABDOMINAL IMAGING 
ISSN
 0942-8925 
Issue Date
2012
MeSH
Adult ; Aged ; Aged, 80 and over ; Bile Ducts/pathology ; Carcinoma, Hepatocellular/complications ; Carcinoma, Hepatocellular/diagnosis* ; Carcinoma, Hepatocellular/diagnostic imaging ; Carcinoma, Hepatocellular/pathology ; Female ; Hepatitis B, Chronic/complications* ; Hepatitis C, Chronic/complications* ; Humans ; Liver Neoplasms/complications ; Liver Neoplasms/diagnosis* ; Liver Neoplasms/diagnostic imaging ; Male ; Middle Aged ; Neoplasm Invasiveness ; Prognosis ; Radiography ; Retrospective Studies
Keywords
Hepatocellular carcinoma ; Hepatits B virus ; Hepatits C virus ; Computed tomography
Abstract
AIM: To compare clinical and radiological findings of newly diagnosed hepatocellular carcinomas (HCCs) in patients with chronic hepatitis B virus (HBV) and chronic hepatitis C virus (HCV) infections. MATERIALS AND METHODS: Dynamic contrast-enhanced CT images in 532 patients with newly diagnosed HCC were retrospectively reviewed. Of these patients, 418 had chronic HBV infections and 114 had chronic HCV infections. The number, size, shape (nodular vs. non-nodular) and enhancement pattern (typical vs. atypical) of hepatic lesions were assessed. The presence of portal vein thrombosis and bile duct invasion were determined. RESULTS: The mean age of the HBV group (54.31 [range 27-85], median 54) was younger than that of the HCV group (64.21 [range 30-86], median 64) (P < 0.001). Lesions in patients with HBV were more likely to be multifocal (>5; P < 0.001); larger than 5 cm (P = 0.023); non-nodular shape (P < 0.001); atypical enhancement pattern (P = 0.047), association with portal vein thrombosis (P = 0.004); association with bile duct invasion (P < 0.001). CONCLUSIONS: Clinical and radiological findings of HCC differ between patients with HBV and HCV infections.
Full Text
http://link.springer.com/article/10.1007%2Fs00261-011-9799-5
DOI
21910010
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Kyung Eun(김경은)
Kim, Ki Whang(김기황)
Kim, Myeong Jin(김명진) ORCID logo https://orcid.org/0000-0001-7949-5402
Park, Mi-Suk(박미숙) ORCID logo https://orcid.org/0000-0001-5817-2444
Baek, Song Ee(백송이) ORCID logo https://orcid.org/0000-0001-8146-2570
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/89341
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