A clinical trial is a prospective experimental study carried out on human subjects, which is designed to evaluate the effects of specific intervention by comparing the study with the control group. In recent years, clinical trials have gained extreme popularity and have become imperative in the field of radiology. In the present work, we introduce the content of panel discussion at first clinical trial workshop of Korean Society of Radiology. This study will help the members of Korean Society of Radiology to be acquainted and facilitated with clinical trials.