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Carcinoma ex pleomorphic Adenoma in the Oral Cavity: A Huge Oral Cavity Mass With Neck Metastasis

Authors
 Hyun Jun Hong  ;  Hyung Kwon Byeon  ;  Seong Hoon Bae  ;  Ah Young Park  ;  Eun Chang Choi  ;  Hong-Shik Choi 
Citation
 JOURNAL OF CRANIOFACIAL SURGERY, Vol.24(6) : 543-546, 2013 
Journal Title
 JOURNAL OF CRANIOFACIAL SURGERY 
ISSN
 1049-2275 
Issue Date
2013
MeSH
Adenocarcinoma/diagnosis* ; Adenocarcinoma/secondary ; Adenoma, Pleomorphic/diagnosis* ; Adenoma, Pleomorphic/pathology ; Aged ; Follow-Up Studies ; Humans ; Lymphatic Metastasis/diagnosis* ; Male ; Neck Dissection ; Neoplasm Invasiveness ; Neoplasm Staging ; Palatal Neoplasms/diagnosis* ; Salivary Gland Neoplasms/diagnosis*
Keywords
Carcinoma ex pleomorphic adenoma ; oral cavity mass ; neck metastasis
Abstract
Carcinoma ex pleomorphic adenoma (CEPA) is a rare, aggressive, poorly understood malignancy. In CEPA, an epithelial malignancy develops in association with a primary or recurrent benign pleomorphic adenoma. Carcinoma ex pleomorphic adenoma is very difficult to identify before surgery because the clinical presentation of many cases is similar to that of pleomorphic adenomas. The risk for malignancy increases with the duration of a mixed tumor. Treatment of CEPA must be individualized on the basis of the tumor location, involvement of adjacent structures, histologic subtype, and grade. The authors recently experienced a case of CEPA arising in the oral cavity with neck metastasis. The patient was a 70-year-old man presenting a huge mass that was present for 20 years and that slowly grew on the left side of the neck. We treated it with a total excision with wide margins and neck dissection. There was no recurrence during the follow-up period of 5 years up until now. We present a case of an unusually huge CEPA in the oral cavity.
Full Text
http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00001665-201311000-00099&LSLINK=80&D=ovft
DOI
10.1097/SCS.0b013e31829ac5f9
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Otorhinolaryngology (이비인후과학교실) > 1. Journal Papers
Yonsei Authors
Bae, Seong Hoon(배성훈)
Byeon, Hyung Kwon(변형권)
Choi, Eun Chang(최은창)
Choi, Hong Shik(최홍식)
Hong, Hyun Jun(홍현준)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/88931
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