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Age-related changes in liver, kidney, and spleen stiffness in healthy children measured with acoustic radiation force impulse imaging

 Mi-Jung Lee ; Myung-Joon Kim ; Choon Sik Yoon ; Kyung Hwa Han 
 European Journal of Radiology, Vol.82(6) : e290~e294, 2013 
Journal Title
 European Journal of Radiology 
Issue Date
OBJECTIVES: To evaluate the feasibility and age-related changes of shear wave velocity (SWV) in normal livers, kidneys, and spleens of children using acoustic radiation force impulse (ARFI) imaging. MATERIALS AND METHODS: Healthy pediatric volunteers prospectively underwent abdominal ultrasonography and ARFI. The subjects were divided into three groups according to age: group 1: <5 years old; group 2: 5-10 years old; and group 3: >10 years old. The SWV was measured using a 4-9 MHz linear probe for group 1 and a 1-4 MHz convex probe for groups 2 and 3. Three valid SWV measurements were acquired for each organ. RESULTS: Two hundred and two children (92 male, 110 female) with an average age of 8.1 years (± 4.7) were included in this study and had a successful measurement rate of 97% (196/202). The mean SWVs were 1.12 m/s for the liver, 2.19 m/s for the right kidney, 2.33 m/s for the left kidney, and 2.25 m/s for the spleen. The SWVs for the right and left kidneys, and the spleen showed age-related changes in all children (p<0.001). And the SWVs for the kidneys increased with age in group 1, and those for the liver changed with age in group 3. CONCLUSIONS: ARFI measurements are feasible for solid abdominal organs in children using high or low frequency probes. The mean ARFI SWV for the kidneys increased according to age in children less than 5 years of age and in the liver, it changed with age in children over 10.
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Radiology
1. 연구논문 > 1. College of Medicine > Yonsei Biomedical Research Center
Yonsei Authors
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