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CT Venography for Deep Vein Thrombosis Using a Low Tube Voltage (100 kVp) Setting Could Increase Venous Enhancement and Reduce the Amount of Administered Iodine

 Eun-Suk Cho  ;  Jae-Joon Chung  ;  Sungjun Kim  ;  Joo Hee Kim  ;  Jeong-Sik Yu  ;  Choon-Sik Yoon 
 Korean Journal of Radiology, Vol.14(2) : 183-193, 2013 
Journal Title
 Korean Journal of Radiology 
Issue Date
OBJECTIVE: To investigate the validity of the 100 kVp setting in CT venography (CTV) in the diagnosis of deep vein thrombosis (DVT), and to evaluate the feasibility of reducing the amount of administered iodine in this setting. MATERIALS AND METHODS: After receiving the contrast medium (CM) of 2.0 mL/kg, 88 patients underwent CTV of the pelvis and lower extremities by using one of four protocols: Group A, 120 kVp setting and 370 mgI/mL CM; group B, 120 kVp and 300 mgI/mL; group C, 100 kVp and 370 mgI/mL; group D, 100 kVp and 300 mgI/mL. The groups were evaluated for venous attenuation, vein-to-muscle contrast-to-noise ratio (CNR(VEIN)), DVT-to-vein contrast-to-noise ratio (CNR(DVT)), and subjective degree of venous enhancement and image quality. RESULTS: Venous attenuation and CNR(VEIN) were significantly higher in group C (144.3 Hounsfield unit [HU] and 11.9), but there was no significant difference between group A (118.0 HU and 8.2) and D (122.4 HU and 7.9). The attenuation value of DVT was not significantly different among the four groups, and group C had a higher absolute CNR(DVT) than the other groups. The overall diagnostic image quality and venous enhancement were significantly higher in group C, but there was no difference between groups A and D. CONCLUSION: The 100 kVp setting in CTV substantially help improve venous enhancement and CNR(VEIN). Furthermore, it enables to reduce the amount of administered iodine while maintaining venous attenuation, as compared with the 120 kVp setting.
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1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
김성준(Kim, Sungjun) ORCID logo https://orcid.org/0000-0002-7876-7901
김주희(Kim, Joo Hee) ORCID logo https://orcid.org/0000-0001-5383-3602
유정식(Yu, Jeong Sik) ORCID logo https://orcid.org/0000-0002-8171-5838
윤춘식(Yoon, Choon Sik) ORCID logo https://orcid.org/0000-0003-2010-6710
정재준(Chung, Jae Joon) ORCID logo https://orcid.org/0000-0002-7447-1193
조은석(Cho, Eun Suk)
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