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Repeated Thrombolytic Therapy in Patients with Recurrent Acute Ischemic Stroke
DC Field | Value | Language |
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dc.contributor.author | 송태진 | - |
dc.contributor.author | 이혜선 | - |
dc.contributor.author | 허지회 | - |
dc.contributor.author | 김동익 | - |
dc.contributor.author | 김동준 | - |
dc.contributor.author | 김병문 | - |
dc.contributor.author | 김영대 | - |
dc.contributor.author | 남효석 | - |
dc.contributor.author | 송동범 | - |
dc.contributor.author | 유한수 | - |
dc.date.accessioned | 2014-12-18T09:19:24Z | - |
dc.date.available | 2014-12-18T09:19:24Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 2287-6391 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/87956 | - |
dc.description.abstract | Background and Purpose Widespread use of thrombolytic treatments, along with improved chances of survival after an initial ischemic stroke, increases the possibility of repeated thrombolysis. There are few reports, however, regarding repeated thrombolysis in patients who have suffered acute ischemic stroke. We explored the number and outcome of patients with repeated thrombolytic therapy in the era of multimodal thrombolytic treatments. Methods We investigated patients with acute ischemic stroke who had received thrombolytic treatments for a period of 10 years. Number of thrombolysis was determined in each patient. Recanalization was defined as Thrombolysis in Cerebral Infarction grading ≥2a. Symptomatic hemorrhagic transformation was defined as any increase in the National Institutes of Health Stroke Scale score that could be attributed to intracerebral hemorrhage. A good outcome was defined as a modified Rankin scale score ≤2. Results Of the 437 patients who received thrombolytic treatments, only 7 underwent repeated thrombolysis (1.6%). The median age at the time of repeated thrombolytic therapy was 71 years old; 4 of the patients were female. All patients had 1 or more potential sources of cardiac embolism. Recanalization was achieved in all patients, in both the first and the second thrombolysis. No symptomatic intracranial hemorrhage occurred after repeated thrombolytic treatments. Five patients (71.4%) showed good outcomes at 3 months. Conclusions Repeated thrombolysis for recurrent acute ischemic stroke appears to be safe and feasible. Among patients who experience recurrent acute ischemic stroke, thrombolytic therapy could be considered even if the patient has had previous thrombolytic treatments. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.relation.isPartOf | JOURNAL OF STROKE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Repeated Thrombolytic Therapy in Patients with Recurrent Acute Ischemic Stroke | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Neurology (신경과학) | - |
dc.contributor.googleauthor | Han Soo Yoo | - |
dc.contributor.googleauthor | Young Dae Kim | - |
dc.contributor.googleauthor | Hye Sun Lee | - |
dc.contributor.googleauthor | Dongbeom Song | - |
dc.contributor.googleauthor | Tae Jin Song | - |
dc.contributor.googleauthor | Byung Moon Kim | - |
dc.contributor.googleauthor | Dong Joon Kim | - |
dc.contributor.googleauthor | Dong Ik Kim | - |
dc.contributor.googleauthor | Ji Hoe Heo | - |
dc.contributor.googleauthor | Hyo Suk Nam | - |
dc.identifier.doi | 10.5853/jos.2013.15.3.182 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02073 | - |
dc.contributor.localId | A04369 | - |
dc.contributor.localId | A00408 | - |
dc.contributor.localId | A00410 | - |
dc.contributor.localId | A00498 | - |
dc.contributor.localId | A00702 | - |
dc.contributor.localId | A01273 | - |
dc.contributor.localId | A02017 | - |
dc.contributor.localId | A03312 | - |
dc.relation.journalcode | J01758 | - |
dc.identifier.eissn | 2287-6405 | - |
dc.identifier.pmid | 24396812 | - |
dc.subject.keyword | Acute ischemic stroke | - |
dc.subject.keyword | Outcome | - |
dc.subject.keyword | Recurrence | - |
dc.subject.keyword | Thrombolysis | - |
dc.contributor.alternativeName | Song, Tae Jin | - |
dc.contributor.alternativeName | Lee, Hye Sun | - |
dc.contributor.alternativeName | Heo, Ji Hoe | - |
dc.contributor.alternativeName | Kim, Dong Ik | - |
dc.contributor.alternativeName | Kim, Dong Joon | - |
dc.contributor.alternativeName | Kim, Byung Moon | - |
dc.contributor.alternativeName | Kim, Young Dae | - |
dc.contributor.alternativeName | Nam, Hyo Suk | - |
dc.contributor.alternativeName | Song, Dong Beom | - |
dc.contributor.affiliatedAuthor | Song, Tae Jin | - |
dc.contributor.affiliatedAuthor | Heo, Ji Hoe | - |
dc.contributor.affiliatedAuthor | Kim, Dong Ik | - |
dc.contributor.affiliatedAuthor | Kim, Dong Joon | - |
dc.contributor.affiliatedAuthor | Kim, Byung Moon | - |
dc.contributor.affiliatedAuthor | Kim, Young Dae | - |
dc.contributor.affiliatedAuthor | Nam, Hyo Suk | - |
dc.contributor.affiliatedAuthor | Song, Dong Beom | - |
dc.contributor.affiliatedAuthor | Lee, Hye Sun | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 15 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 182 | - |
dc.citation.endPage | 188 | - |
dc.identifier.bibliographicCitation | JOURNAL OF STROKE, Vol.15(3) : 182-188, 2013 | - |
dc.identifier.rimsid | 33872 | - |
dc.type.rims | ART | - |
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