Associations of Moderate to Severe Asthma with Obstructive Sleep Apnea

456 1306

Cited 0 times in

Cited 17 times in

Authors: Min Kwang Byun ; Seon Cheol Park ; Yoon Soo Chang ; Young Sam Kim ; Se Kyu Kim ; Hyung Jung Kim ; Joon Chang ; Chul Min Ahn ; Moo Suk Park

MeSH: Aged ; Asthma/complications ; Asthma/epidemiology ; Asthma/etiology* ; Comorbidity ; Cross-Sectional Studies ; Female ; Humans ; Male ; Middle Aged ; Polysomnography/instrumentation ; Severity of Illness Index ; Sleep Apnea Syndromes/epidemiology ; Sleep Apnea Syndromes/etiology ; Sleep Apnea, Obstructive/complications ; Sleep Apnea, Obstructive/epidemiology ; Sleep Apnea, Obstructive/physiopathology*

Keywords: Apnea-hypopnea index ; ApneaLink ; asthma ; obstructive sleep apnea ; sleep-disordered breathing

Abstract: PURPOSE:
This study aimed to evaluate the correlation between associating factors of moderate to severe asthma with obstructive sleep apnea (OSA).
MATERIALS AND METHODS:
One hundred and sixty-seven patients who visited the pulmonary and sleep clinic in Severance Hospital presenting with symptoms of sleep-disordered breathing were evaluated. All subjects were screened with ApneaLink. Thirty-two subjects with a high likelihood of having OSA were assessed with full polysomnography (PSG).
RESULTS:
The mean age was 58.8±12.0 years and 58.7% of subjects were male. The mean ApneaLink apnea-hypopnea index (AHI) was 12.7±13.0/hr. The mean ApneaLink AHI for the 32 selected high risk patients of OSA was 22.3±13.2/hr, which was lower than the sleep laboratory-based PSG AHI of 39.1±20.5/hr. When OSA was defined at an ApneaLink AHI≥5/hr, the positive correlating factors for OSA were age, male gender, and moderate to severe asthma.
CONCLUSION:
Moderate to severe asthma showed strong correlation with OSA when defined at an ApneaLink AHI≥5/hr.