620 809

Cited 0 times in

법의 분야에서 DNA 메틸화를 이용한 연령 추정

Other Titles
 DNA Methylation-Based Age Estimation in the Forensic Field 
 안자현  ;  신경진  ;  최아진  ;  양우익  ;  이환영 
 Korean Journal of Legal Medicine (대한법의학회지), Vol.37(1) : 1-8, 2013 
Journal Title
Korean Journal of Legal Medicine(대한법의학회지)
Issue Date
DNA methylation ; Age estimation ; Epigenetics ; Forensics
The estimation of age is an important issue in forensic science, and the forensic community has attempted many times to establish methods for solving this issue. Aging leads to alterations in tissues and organs at the molecular level. These alterations at the molecular level may aid forensic scientists to estimate the age of a living person or a dead body. Initially, the focus was on the genetic components of aging, but recently, epigenetic mechanisms have emerged as the key contributors to the alterations in genome structure and function that accompany aging. In particular, DNA methylation is one of the best-understood mechanisms, and it has been suggested as a promising biomarker for age estimation in many studies. In this review, we summarize the recent studies on age-associated DNA methylation changes in different tissues and discuss its possible and practical applications in forensics.
Files in This Item:
T201302629.pdf Download
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Forensic Medicine (법의학과) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
Yonsei Authors
Shin, Kyoung Jin(신경진) ORCID logo https://orcid.org/0000-0002-1059-9665
An, Ja Hyun(안자현)
Yang, Woo Ick(양우익) ORCID logo https://orcid.org/0000-0002-6084-5019
Lee, Hwan Young(이환영)
Choi, A Jin(최아진)
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.