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법의 분야에서 DNA 메틸화를 이용한 연령 추정
DC Field | Value | Language |
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dc.contributor.author | 신경진 | - |
dc.contributor.author | 안자현 | - |
dc.contributor.author | 양우익 | - |
dc.contributor.author | 이환영 | - |
dc.contributor.author | 최아진 | - |
dc.date.accessioned | 2014-12-18T09:04:30Z | - |
dc.date.available | 2014-12-18T09:04:30Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 1225-0589 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/87485 | - |
dc.description.abstract | The estimation of age is an important issue in forensic science, and the forensic community has attempted many times to establish methods for solving this issue. Aging leads to alterations in tissues and organs at the molecular level. These alterations at the molecular level may aid forensic scientists to estimate the age of a living person or a dead body. Initially, the focus was on the genetic components of aging, but recently, epigenetic mechanisms have emerged as the key contributors to the alterations in genome structure and function that accompany aging. In particular, DNA methylation is one of the best-understood mechanisms, and it has been suggested as a promising biomarker for age estimation in many studies. In this review, we summarize the recent studies on age-associated DNA methylation changes in different tissues and discuss its possible and practical applications in forensics. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | Korean Journal of Legal Medicine (대한법의학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | 법의 분야에서 DNA 메틸화를 이용한 연령 추정 | - |
dc.title.alternative | DNA Methylation-Based Age Estimation in the Forensic Field | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pathology (병리학) | - |
dc.contributor.googleauthor | 안자현 | - |
dc.contributor.googleauthor | 신경진 | - |
dc.contributor.googleauthor | 최아진 | - |
dc.contributor.googleauthor | 양우익 | - |
dc.contributor.googleauthor | 이환영 | - |
dc.identifier.doi | 10.7580/kjlm.2013.37.1.1 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02085 | - |
dc.contributor.localId | A02254 | - |
dc.contributor.localId | A02300 | - |
dc.contributor.localId | A03335 | - |
dc.contributor.localId | A04106 | - |
dc.relation.journalcode | J02046 | - |
dc.identifier.pmid | DNA methylation ; Age estimation ; Epigenetics ; Forensics | - |
dc.subject.keyword | DNA methylation | - |
dc.subject.keyword | Age estimation | - |
dc.subject.keyword | Epigenetics | - |
dc.subject.keyword | Forensics | - |
dc.contributor.alternativeName | Shin, Kyoung Jin | - |
dc.contributor.alternativeName | An, Ja Hyun | - |
dc.contributor.alternativeName | Yang, Woo Ick | - |
dc.contributor.alternativeName | Lee, Hwan Young | - |
dc.contributor.alternativeName | Choi, A Jin | - |
dc.contributor.affiliatedAuthor | Shin, Kyoung Jin | - |
dc.contributor.affiliatedAuthor | An, Ja Hyun | - |
dc.contributor.affiliatedAuthor | Yang, Woo Ick | - |
dc.contributor.affiliatedAuthor | Lee, Hwan Young | - |
dc.contributor.affiliatedAuthor | Choi, A Jin | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 37 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 8 | - |
dc.identifier.bibliographicCitation | Korean Journal of Legal Medicine (대한법의학회지), Vol.37(1) : 1-8, 2013 | - |
dc.identifier.rimsid | 34256 | - |
dc.type.rims | ART | - |
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