2 69

Cited 6 times in

Stereotactic Body Radiotherapy with Helical Tomotherapy for Pain Palliation in Spine Metastasis

Authors
 M. S. Kim ; K. C. Keum ; W. S. Koom ; K. C. Nam ; C. G. Lee ; J. S. Seong ; J. H. Kim ; J. H. Cha 
Citation
 Technology in Cancer Research & Treatment, Vol.12(4) : 363~370, 2013 
Journal Title
 Technology in Cancer Research & Treatment 
ISSN
 1533-0346 
Issue Date
2013
Abstract
To evaluate the pain response, local tumor control and toxicity of stereotactic body radiotherapy (SBRT) with helical tomotherapy (HT) in the patients with spine metastasis. From May 2009 to June 2010, 22 patients with 31 lesions were treated by SBRT. Dose scheme were 24 Gy in 3 fractions (87.1%), 30 Gy in 5 fractions (9.7%), and 16 Gy in a single fraction (3.2%). Pain was assessed using a numerical rating scale. Analgesic consumption was recalculated into the daily oral morphine-equivalent dose (OMED). The response criteria of International Bone Metastases Consensus Group (IBMCG) was used. The median follow-up duration was 10 months (range 3-23 months). After SBRT the mean pain score decreased significantly (4.32 before SBRT, 0.71 at 3 months). However, median OMED didn't decrease until 3 months after SBRT (Median OMED; 34.5 mg before SBRT, 45 mg at 3 months). Pain response rate and pain progression-free survival rate at 3 month was 96.8 and 93.5%, respectively. Local progression-free survival rate at 3 month was 93.5%. There was no severe acute toxicity. SBRT with HT is a safe and effective treatment modality for local tumor control and pain palliation associated with spine metastasis.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/87180
DOI
10.7785/tcrt.2012.500329
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Medical Engineering
1. 연구논문 > 1. College of Medicine > Dept. of Radiation Oncology
1. 연구논문 > 1. College of Medicine > Yonsei Biomedical Research Center
Yonsei Authors
사서에게 알리기
  feedback
Link
 http://www.tcrt.org/product-p18032.html
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse