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Catch-up growth after long-term implementation and weaning from ketogenic diet in pediatric epileptic patients

Authors
 Jeong Tae Kim  ;  Hoon-Chul Kang  ;  Ji-Eun Song  ;  Min Jung Lee  ;  Yun Jin Lee  ;  Eun Joo Lee  ;  Joon Soo Lee  ;  Heung Dong Kim 
Citation
 Clinical Nutrition, Vol.32(1) : 98-103, 2013 
Journal Title
 Clinical Nutrition 
ISSN
 0261-5614 
Issue Date
2013
Abstract
BACKGROUND & AIMS: To assess the presence of growth retardation during long-term implementation of ketogenic diet (KD) among children with epilepsy, and verify the presence of catch-up growth in same patients 1 year after diet discontinuation. METHODS: Retrospective chart review of 20 males and 20 females was performed and z scores of height, weight and body mass index was obtained at baseline, 2 years into KD, and 1 year after discontinuation of KD. RESULTS: Our analysis revealed significant reduction in both height and weight gain among children with epilepsy after prolonged KD. After a year of diet discontinuation, significant catch-up growth was evident in both height and weight. In regard to specific subsets, ambulation had favorable influence on growth during KD and after diet discontinuation. Uncontrolled epilepsy, and younger age at the start of KD contributed a negative impact on a child's growth. CONCLUSIONS: This preliminary observation into long-term growth pattern among recipients of KD will aid both health care providers and patients alike in planning for long-term care extending beyond the duration of dietary treatment.
Full Text
http://www.sciencedirect.com/science/article/pii/S0261561412001197
DOI
10.1016/j.clnu.2012.05.019
Appears in Collections:
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pharmacology (약리학교실) > 1. Journal Papers
Yonsei Authors
강훈철(Kang, Hoon Chul) ORCID logo https://orcid.org/0000-0002-3659-8847
김흥동(Kim, Heung Dong) ORCID logo https://orcid.org/0000-0002-8031-7336
이민정(Lee, Min Jung)
이윤진(Lee, Yun Jin)
이은주(Lee, Eun Joo)
이준수(Lee, Joon Soo) ORCID logo https://orcid.org/0000-0001-9036-9343
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/87086
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