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MR-DWI–Positive Lesions and Symptomatic Ischemic Complications After Coiling of Unruptured Intracranial Aneurysms

Authors
 Dong-Hun Kang  ;  Byung Moon Kim  ;  Dong Joon Kim  ;  Sang Hyun Suh  ;  Dong Ik Kim  ;  Yong-Sun Kim  ;  Seung Kon Huh  ;  Jaechan Park  ;  Jae Whan Lee  ;  Yong Bae Kim 
Citation
 STROKE, Vol.44(3) : 789-791, 2013 
Journal Title
 STROKE 
ISSN
 0039-2499 
Issue Date
2013
MeSH
Age Factors ; Aged ; Aged, 80 and over ; Diffusion Magnetic Resonance Imaging* ; Embolization, Therapeutic/adverse effects* ; Embolization, Therapeutic/instrumentation ; Embolization, Therapeutic/methods ; Female ; Humans ; Incidence ; Intracranial Aneurysm/therapy* ; Ischemic Attack, Transient/epidemiology* ; Ischemic Attack, Transient/pathology* ; Male ; Middle Aged ; Retrospective Studies ; Risk Factors ; Sensitivity and Specificity ; Stroke/epidemiology* ; Stroke/pathology*
Keywords
Age Factors ; Aged ; Aged, 80 and over ; Diffusion Magnetic Resonance Imaging* ; Embolization, Therapeutic/adverse effects* ; Embolization, Therapeutic/instrumentation ; Embolization, Therapeutic/methods ; Female ; Humans ; Incidence ; Intracranial Aneurysm/therapy* ; Ischemic Attack, Transient/epidemiology* ; Ischemic Attack, Transient/pathology* ; Male ; Middle Aged ; Retrospective Studies ; Risk Factors ; Sensitivity and Specificity ; Stroke/epidemiology* ; Stroke/pathology*
Abstract
BACKGROUND AND PURPOSE: The aims of this study are to evaluate the risk factors for symptomatic ischemic complication (symptomatic ischemic complication [SIC], transient ischemic attack, or stroke) and microembolisms detected as MR diffusion-weighted imaging (MR-DWI)-positive (DWI(+)) lesions, and the relationship between DWI(+) and SIC after coiling of unruptured intracranial aneurysm. METHODS: Between March 2009 and November 2011, 382 unruptured intracranial aneurysms in 343 patients underwent both coiling and posttreatment MR-DWI. The incidence of and risk factors for SIC and DWI(+), and the relationship between DWI(+) and SIC were retrospectively analyzed. RESULTS: The incidence of SIC was 4.1%. The incidence of DWI(+) was 54.5%. The number of DWI(+) lesions was significantly larger in the SIC group, than in the asymptomatic one (12.1±10.4 versus 5.0±8.7, P<0.00). The cutoff value of DWI(+) for predicting SIC was ≥6 (sensitivity 85.7%, specificity 70.7%). The patients with DWI(+) ≥6 was 28.6%. Of the patients with SIC, the patients with DWI(+) ≥6 was 78.6%. Patients aged≥65 years had a trend for SIC, and it was the only independent risk factor for DWI(+) ≥cutoff (n=6; 95%CI, 1.167-3.083). CONCLUSIONS: The number of DWI(+) lesions was significantly larger in the SIC group than in the asymptomatic one after coiling of unruptured intracranial aneurysm. Patients aged≥65 had a trend for SIC, and it was the only independent risk factor for the number of DWI(+) ≥cutoff value (n=6) for predicting SIC.
Files in This Item:
T201300649.pdf Download
DOI
10.1161/STROKEAHA.112.669853
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Dong Ik(김동익)
Kim, Dong Joon(김동준) ORCID logo https://orcid.org/0000-0002-7035-087X
Kim, Byung Moon(김병문) ORCID logo https://orcid.org/0000-0001-8593-6841
Kim, Yong Bae(김용배) ORCID logo https://orcid.org/0000-0003-2262-7157
Suh, Sang Hyun(서상현) ORCID logo https://orcid.org/0000-0002-7098-4901
Lee, Jae Whan(이재환)
Huh, Seung Kon(허승곤)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/86553
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