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Feasibility study for dose calculation with a radiation treatment planning system using a fixed-size electron cone applicator for small electron fields

Authors
 Su Chul Han  ;  Min Cheol Han  ;  Jihun Kim  ;  Heerim Nam  ;  Jin Sung Kim  ;  Kwangwoo Park 
Citation
 PLOS ONE, Vol.20(8) : e0324722, 2025-08 
Journal Title
PLOS ONE
Issue Date
2025-08
MeSH
Electrons* / therapeutic use ; Feasibility Studies ; Humans ; Phantoms, Imaging ; Radiometry / methods ; Radiotherapy Dosage ; Radiotherapy Planning, Computer-Assisted* / methods
Abstract
Objective: This study aims to evaluate the feasibility of radiation treatment planning using a commercial treatment planning system (TPS) for small fixed-size electron cone electron applicators not natively supported by the TPS.

Methods: Dosimetric characteristics, including beam profiles and output factors (OFs), were compared between a 6 MeV electron beam collimated by a small fixed-size electron cone applicator and a cerrobend cutout-based general applicator. Measurements were performed using a micro-diamond detector in a water phantom for field sizes of 2, 3, 4, and 5 cm. The monitor units (MUs) from the TPS were compared with direct measurements. To estimate the MU for the fixed-size electron cone applicator using the TPS, the relative OFs were defined as the ratio of the OFs for the fixed-size electron cone and general applicators. Dose distributions obtained from the TPS were validated against measurements using Gafchromic films, ensuring accuracy.

Results: Gamma analysis showed a passing rate >95% with 1%/1 mm criteria for depth dose comparisons and >99% with 2%/2 mm criteria for beam profiles. The general applicator's OFs were consistently higher across all measured field sizes. The MU difference between the TPS and measurements was within 2.0%, while the difference between indirect TPS calculations and direct measurements for the fixed-size electron cone applicator remained within 1.0%. Dose distribution analysis showed >99% agreement (3%/3 mm) between the 2D dose distribution obtained using film in the fixed-size electron cone applicator and that calculated by the TPS of cerrobend cutout-based applicator.

Conclusion: The results demonstrate the feasibility of calculating monitor units and dose distributions for small fixed-size electron cone applicators using a commercial TPS combined with relative output factors. This approach offers a reliable method for dose calculation in specialized electron therapy applications.
Files in This Item:
T202505821.pdf Download
DOI
10.1371/journal.pone.0324722
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers
Yonsei Authors
Kim, Jihun(김지훈) ORCID logo https://orcid.org/0000-0003-4856-6305
Kim, Jinsung(김진성) ORCID logo https://orcid.org/0000-0003-1415-6471
Park, Kwang Woo(박광우) ORCID logo https://orcid.org/0000-0002-9843-7985
Han, Min Cheol(한민철)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/207584
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