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Feasibility study for dose calculation with a radiation treatment planning system using a fixed-size electron cone applicator for small electron fields

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dc.contributor.author김지훈-
dc.contributor.author김진성-
dc.contributor.author박광우-
dc.contributor.author한민철-
dc.date.accessioned2025-10-17T07:53:48Z-
dc.date.available2025-10-17T07:53:48Z-
dc.date.issued2025-08-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/207584-
dc.description.abstractObjective: This study aims to evaluate the feasibility of radiation treatment planning using a commercial treatment planning system (TPS) for small fixed-size electron cone electron applicators not natively supported by the TPS. Methods: Dosimetric characteristics, including beam profiles and output factors (OFs), were compared between a 6 MeV electron beam collimated by a small fixed-size electron cone applicator and a cerrobend cutout-based general applicator. Measurements were performed using a micro-diamond detector in a water phantom for field sizes of 2, 3, 4, and 5 cm. The monitor units (MUs) from the TPS were compared with direct measurements. To estimate the MU for the fixed-size electron cone applicator using the TPS, the relative OFs were defined as the ratio of the OFs for the fixed-size electron cone and general applicators. Dose distributions obtained from the TPS were validated against measurements using Gafchromic films, ensuring accuracy. Results: Gamma analysis showed a passing rate >95% with 1%/1 mm criteria for depth dose comparisons and >99% with 2%/2 mm criteria for beam profiles. The general applicator's OFs were consistently higher across all measured field sizes. The MU difference between the TPS and measurements was within 2.0%, while the difference between indirect TPS calculations and direct measurements for the fixed-size electron cone applicator remained within 1.0%. Dose distribution analysis showed >99% agreement (3%/3 mm) between the 2D dose distribution obtained using film in the fixed-size electron cone applicator and that calculated by the TPS of cerrobend cutout-based applicator. Conclusion: The results demonstrate the feasibility of calculating monitor units and dose distributions for small fixed-size electron cone applicators using a commercial TPS combined with relative output factors. This approach offers a reliable method for dose calculation in specialized electron therapy applications.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherPublic Library of Science-
dc.relation.isPartOfPLOS ONE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHElectrons* / therapeutic use-
dc.subject.MESHFeasibility Studies-
dc.subject.MESHHumans-
dc.subject.MESHPhantoms, Imaging-
dc.subject.MESHRadiometry / methods-
dc.subject.MESHRadiotherapy Dosage-
dc.subject.MESHRadiotherapy Planning, Computer-Assisted* / methods-
dc.titleFeasibility study for dose calculation with a radiation treatment planning system using a fixed-size electron cone applicator for small electron fields-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiation Oncology (방사선종양학교실)-
dc.contributor.googleauthorSu Chul Han-
dc.contributor.googleauthorMin Cheol Han-
dc.contributor.googleauthorJihun Kim-
dc.contributor.googleauthorHeerim Nam-
dc.contributor.googleauthorJin Sung Kim-
dc.contributor.googleauthorKwangwoo Park-
dc.identifier.doi10.1371/journal.pone.0324722-
dc.contributor.localIdA05823-
dc.contributor.localIdA04548-
dc.contributor.localIdA01432-
dc.contributor.localIdA05870-
dc.relation.journalcodeJ02540-
dc.identifier.eissn1932-6203-
dc.identifier.pmid40811639-
dc.contributor.alternativeNameKim, Jihun-
dc.contributor.affiliatedAuthor김지훈-
dc.contributor.affiliatedAuthor김진성-
dc.contributor.affiliatedAuthor박광우-
dc.contributor.affiliatedAuthor한민철-
dc.citation.volume20-
dc.citation.number8-
dc.citation.startPagee0324722-
dc.identifier.bibliographicCitationPLOS ONE, Vol.20(8) : e0324722, 2025-08-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers

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