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Polynucleotides in Aesthetic Medicine: A Review of Current Practices and Perceived Effectiveness

Authors
 Kar Wai Alvin Lee  ;  Kwin Wah Lisa Chan  ;  Angela Lee  ;  Cheuk Hung Lee  ;  Jovian Wan  ;  Sky Wong  ;  Kyu-Ho Yi 
Citation
 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, Vol.25(15) : 8224, 2024-08 
Journal Title
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
ISSN
 1661-6596 
Issue Date
2024-08
MeSH
Cosmetic Techniques ; Esthetics ; Humans ; Polynucleotides* / therapeutic use ; Skin Aging / drug effects
Keywords
aesthetic medicine ; cosmetic medicine ; facial appearance ; polynucleotides ; skin texture ; wrinkle depth
Abstract
Polynucleotides, complex molecules composed of nucleotides, have gained attention in aesthetic medicine for their potential to regulate gene expression and promote tissue regeneration. This review aims to provide an overview of the current practices and perceived effectiveness of polynucleotides in aesthetic medicine. A comprehensive search of the literature was conducted using keywords related to polynucleotides, cosmetic application, and aesthetic application. Studies were selected based on their relevance to aesthetic medicine and the inclusion of human subjects. The review found that polynucleotides have been used to improve skin texture, reduce wrinkle depth, and enhance facial appearance. The studies reported varying degrees of efficacy and safety, with some studies demonstrating significant improvements in skin elasticity and hydration. However, others reported limited or no benefits. The review also highlighted the need for further research to establish the optimal use and efficacy of polynucleotides in aesthetic medicine. While the existing literature suggests that polynucleotides may have potential benefits in aesthetic medicine, more research is needed to fully understand their mechanisms of action and optimal use. Clinicians should be aware of the current limitations and potential risks associated with the use of polynucleotides in aesthetic medicine.
Files in This Item:
T992024537.pdf Download
DOI
10.3390/ijms25158224
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
Yonsei Authors
Lee, Kyuho(이규호)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/202192
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