60 133

Cited 0 times in

Baseline eGFR cutoff for increased risk of post-contrast acute kidney injury in patients undergoing percutaneous coronary intervention for ST-elevation myocardial infarction in the emergency department

 Je Sung You  ;  Junho Cho  ;  Hye Jung Shin  ;  Jin Ho Beom 
 PLOS ONE, Vol.18(10) : e0293598, 2023-10 
Journal Title
Issue Date
Acute Kidney Injury* / diagnosis ; Acute Kidney Injury* / epidemiology ; Acute Kidney Injury* / etiology ; Contrast Media / adverse effects ; Emergency Service, Hospital ; Glomerular Filtration Rate ; Humans ; Percutaneous Coronary Intervention* / adverse effects ; Percutaneous Coronary Intervention* / methods ; Retrospective Studies ; Risk Factors ; ST Elevation Myocardial Infarction*
Acute myocardial infarction is an acute-stage disease that requires prompt diagnosis and treatment. Primary percutaneous coronary intervention (pPCI) for ST-elevation myocardial infarction (STEMI) is a high-risk factor for post-contrast acute kidney injury (PC-AKI). This retrospective cohort study analyzed the data of 754 patients with STEMI who underwent pPCI and were integrated into the Fast Interrogation Rule for STEMI critical pathway program between 2015 and 2019. We aimed to determine the optimal cutoff baseline eGFR for identifying a high risk of PC-AKI after multivariable adjustment with statistically significant risk factors. We also compared the incidence rates of PC-AKI between the previous and current diagnostic criteria. The probability of PC-AKI increased when the baseline estimated glomerular filtration rate (eGFR) was ≤ 79mL/min/1.73 m2. The optimal cutoff baseline eGFR for high risk of PC-AKI was found to be an eGFR of ≤ 61 mL/min/1.73 m2 after multivariable adjustment. The current diagnostic criteria more accurately identified the patient group with impaired renal function. Our results have clinically significant implications for identifying patients at a high risk of developing PC-AKI, especially before and after the use of contrast agents in patients who require PCI for STEMI in the emergency department.
Files in This Item:
T202306153.pdf Download
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Emergency Medicine (응급의학교실) > 1. Journal Papers
Yonsei Authors
Beom, Jin Ho(범진호) ORCID logo https://orcid.org/0000-0002-2805-257X
You, Je Sung(유제성) ORCID logo https://orcid.org/0000-0002-2074-6745
Cho, Junho(조준호) ORCID logo https://orcid.org/0000-0003-2240-3989
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.