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Baseline eGFR cutoff for increased risk of post-contrast acute kidney injury in patients undergoing percutaneous coronary intervention for ST-elevation myocardial infarction in the emergency department

DC Field Value Language
dc.contributor.author범진호-
dc.contributor.author유제성-
dc.contributor.author조준호-
dc.date.accessioned2023-11-28T03:07:33Z-
dc.date.available2023-11-28T03:07:33Z-
dc.date.issued2023-10-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/196735-
dc.description.abstractAcute myocardial infarction is an acute-stage disease that requires prompt diagnosis and treatment. Primary percutaneous coronary intervention (pPCI) for ST-elevation myocardial infarction (STEMI) is a high-risk factor for post-contrast acute kidney injury (PC-AKI). This retrospective cohort study analyzed the data of 754 patients with STEMI who underwent pPCI and were integrated into the Fast Interrogation Rule for STEMI critical pathway program between 2015 and 2019. We aimed to determine the optimal cutoff baseline eGFR for identifying a high risk of PC-AKI after multivariable adjustment with statistically significant risk factors. We also compared the incidence rates of PC-AKI between the previous and current diagnostic criteria. The probability of PC-AKI increased when the baseline estimated glomerular filtration rate (eGFR) was ≤ 79mL/min/1.73 m2. The optimal cutoff baseline eGFR for high risk of PC-AKI was found to be an eGFR of ≤ 61 mL/min/1.73 m2 after multivariable adjustment. The current diagnostic criteria more accurately identified the patient group with impaired renal function. Our results have clinically significant implications for identifying patients at a high risk of developing PC-AKI, especially before and after the use of contrast agents in patients who require PCI for STEMI in the emergency department.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherPublic Library of Science-
dc.relation.isPartOfPLOS ONE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHAcute Kidney Injury* / diagnosis-
dc.subject.MESHAcute Kidney Injury* / epidemiology-
dc.subject.MESHAcute Kidney Injury* / etiology-
dc.subject.MESHContrast Media / adverse effects-
dc.subject.MESHEmergency Service, Hospital-
dc.subject.MESHGlomerular Filtration Rate-
dc.subject.MESHHumans-
dc.subject.MESHPercutaneous Coronary Intervention* / adverse effects-
dc.subject.MESHPercutaneous Coronary Intervention* / methods-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Factors-
dc.subject.MESHST Elevation Myocardial Infarction*-
dc.titleBaseline eGFR cutoff for increased risk of post-contrast acute kidney injury in patients undergoing percutaneous coronary intervention for ST-elevation myocardial infarction in the emergency department-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Emergency Medicine (응급의학교실)-
dc.contributor.googleauthorJe Sung You-
dc.contributor.googleauthorJunho Cho-
dc.contributor.googleauthorHye Jung Shin-
dc.contributor.googleauthorJin Ho Beom-
dc.identifier.doi10.1371/journal.pone.0293598-
dc.contributor.localIdA05135-
dc.contributor.localIdA02507-
dc.contributor.localIdA03911-
dc.relation.journalcodeJ02540-
dc.identifier.eissn1932-6203-
dc.identifier.pmid37883518-
dc.contributor.alternativeNameBeom, Jin Ho-
dc.contributor.affiliatedAuthor범진호-
dc.contributor.affiliatedAuthor유제성-
dc.contributor.affiliatedAuthor조준호-
dc.citation.volume18-
dc.citation.number10-
dc.citation.startPagee0293598-
dc.identifier.bibliographicCitationPLOS ONE, Vol.18(10) : e0293598, 2023-10-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Emergency Medicine (응급의학교실) > 1. Journal Papers

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