PURPOSE: This study was designed to evaluate usefulness of intravenous digital subtraction angiography(IV-DSA) in detection of peripheral arterial obstructive disease(PAOD) and in follow-up of percutaneoustrasluminal angioplasty(PTA). MATERIALS AND METHODS: 35 patients who had clinical symptoms and signs ofcompromised lower extremity perfusion, was screened with IV-DSA and then performed confirmative conventionalangiography, We obtained sensitivity, specificity and accuracy of IV-DSA by comparing the findigns of IV-DSA withthose of conventional angiography. 21 patents who had been perfomed successful PTA, were followed-up with IV-DSAin 3, 6, 12months. We studied patency rate and factors that influenced restenosis. RESULTS: The sensitivity,specificity and accuracy of IV-DSA were 100%. 97%, 97% in iliac artery, 92%, 96%, 93% in femoropopliteal artery,85%,75%,70% in proximal tibioperoneal artery retrospectively. IV-DSA follow up after PTA showed patency rate of67% in first 3 month, 67% in 2nd 3 month, 60% in nest 6 month. Longer length and more irregular surface of thestenotic site, and higher incidence of run-off of vessel and of residual stenosis in the patients with restenosiswere noted. CONLUSION: High sensitivity, specificity and accuracy of IV-DSA in evaluting PAOD suggest that IV-DSAis useful in screening, planning therapy and following up after PTA.