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Radiation dose reduction using deep learning-based image reconstruction for a low-dose chest computed tomography protocol: a phantom study

Authors
 Yunsub Jung  ;  Jin Hur  ;  Kyunghwa Han  ;  Yasuhiro Imai  ;  Yoo Jin Hong  ;  Dong Jin Im  ;  Kye Ho Lee  ;  Melissa Desnoyers  ;  Brian Thomsen  ;  Risa Shigemasa  ;  Kyounga Um  ;  Kyungeun Jang 
Citation
 QUANTITATIVE IMAGING IN MEDICINE AND SURGERY, Vol.13(3) : 1937-1947, 2023-03 
Journal Title
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
ISSN
 2223-4292 
Issue Date
2023-03
Keywords
Low-dose chest computed tomography (LDCT) ; chest phantom ; deep learning-based image reconstruction (DLIR)
Abstract
Background: The aim of this study was to compare the dose reduction potential and image quality of deep learning-based image reconstruction (DLIR) with those of filtered back-projection (FBP) and iterative reconstruction (IR) and to determine the clinically usable dose of DLIR for low-dose chest computed tomography (LDCT) scans. Methods: Multi-slice computed tomography (CT) scans of a chest phantom were performed with various tube voltages and tube currents, and the images were reconstructed using seven methods to control the amount of noise reduction: FBP, three stages of IR, and three stages of DLIR. For subjective image analysis, four radiologists compared 48 image data sets with reference images and rated on a 5-point scale. For quantitative image analysis, the signal to noise ratio (SNR), contrast to noise ratio (CNR), nodule volume, and nodule diameter were measured. Results: In the subjective analysis, DLIR-Low (0.46 mGy), DLIR-Medium (0.31 mGy), and DLIR-High (0.18 mGy) images showed similar quality to the FBP (2.47 mGy) image. Under the same dose conditions, the SNR and CNR were higher with DLIR-High than with FBP and all the IR methods (all P<0.05). The nodule volume and size with DLIR-High were significantly closer to the real volume than with FBP and all the IR methods (all P<0.001). Conclusions: DLIR can improve the image quality of LDCT compared to FBP and IR. In addition, the appropriate effective dose for LDCT would be 0.24 mGy with DLIR-High. © Quantitative Imaging in Medicine and Surgery. All rights reserved.
Files in This Item:
T202301848.pdf Download
DOI
10.21037/qims-22-618
Appears in Collections:
1. College of Medicine (의과대학) > Research Institute (부설연구소) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Im, Dong Jin(임동진) ORCID logo https://orcid.org/0000-0001-8139-5646
Han, Kyung Hwa(한경화)
Hur, Jin(허진) ORCID logo https://orcid.org/0000-0002-8651-6571
Hong, Yoo Jin(홍유진) ORCID logo https://orcid.org/0000-0002-7276-0944
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/194043
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