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일차진료 클리닉을 방문한 한국인 성인 남녀에서 심박동수변이도와 Triglyceride-Glucose 지수의 연관성

Other Titles
 Relationship of Heart Rate Variability with Triglyceride-Glucose Index among Korean Men and Women in a Primary Care Clinic 
Authors
 류하은  ;  이성범  ;  정동혁  ;  박병진 
Citation
 Korean Journal of Family Practice (가정의학), Vol.12(4) : 274-279, 2022-09 
Journal Title
Korean Journal of Family Practice(가정의학)
ISSN
 2233-9019 
Issue Date
2022-09
Keywords
Heart Rate Variability ; Autonomic Dysfunction ; Triglyceride-Glucose Index ; Insulin Resistance
Abstract
Background: Reduced heart rate variability (HRV) can be a predictor of all causes of death. Few studies have analyzed the association between HRV and the triglyceride-glucose (TyG) index in a primary care setting rather than in specific high-risk patients. This study aimed to investigate the relationship between HRV and the TyG index among Koreans at a primary care clinic.
Methods: This cross-sectional study included 1,991 participants who underwent HRV assessments and blood tests after fasting for more than 8 hours. Common HRV indices such as the standard deviation of normal-to-normal intervals (SDNN), the root mean square of successive difference (RMSSD), total power (TP), low frequency (LF), high frequency (HF), and the LF/HF ratio were measured. Individuals with a TyG index greater than 9.1 (≥75th percentile) were subclassified into a “high TyG index” group. Associations between the TyG index and HRV were investigated using multiple logistic regression analysis.
Results: The individuals’ mean age was 46.6 years, and the high TyG index group included 244 of all 1,991 participants. Among the assessed HRV indices, the SDNN, RMSSD, and HF showed associations with the high TyG index group, with odd ratios of 0.98 (0.97–0.99), 0.98 (0.96–0.99), and 0.99 (0.99–1.00), respectively, after adjusting for age, sex, white blood cell count, total cholesterol, high density lipoprotein cholesterol, alanine aminotransferase, γ-glutamyltransferase, uric acid, creatinine, hypertension, and diabetes.
Conclusion: Among the common HRV indices, the SDNN, RMSSD, and HF were decreased in a subgroup of individuals with a high TyG index.
Files in This Item:
T202204271.pdf Download
DOI
10.21215/kjfp.2022.12.4.274
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Family Medicine (가정의학교실) > 1. Journal Papers
Yonsei Authors
Park, Byoungjin(박병진) ORCID logo https://orcid.org/0000-0003-1733-5301
Jung, Dong Hyuk(정동혁) ORCID logo https://orcid.org/0000-0002-3411-0676
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/191953
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