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Stromal vascular fraction injection to treat intractable radiation-induced rectovaginal fistula

Authors
 Mijung Kim  ;  Dae Hyun Lew  ;  Tai Suk Roh  ;  Seung Yong Song 
Citation
 Archives of Plastic Surgery, Vol.48(1) : 127-130, 2021-01 
Journal Title
Archives of Plastic Surgery
ISSN
 2234-6163 
Issue Date
2021-01
Keywords
Fat graft ; Mesenchymal stem cell ; Radiation effect ; Rectovaginal fistula
Abstract
Rectovaginal fistula, which can arise after an injury to the vaginal canal or rectum, is a troublesome obstacle for patients' everyday life. In most cases, it can be covered with a local flap, but previous radiation therapy increases the recurrence rate, making it especially difficult to cure. As the application of stromal vascular fraction (SVF) obtained from enzymatically digested autologous adipose tissue has become increasingly common, several reports have advocated its effectiveness for the treatment of refractory wounds. In light of the angiogenic, regenerative characteristics of SVF, it was incorporated as a treatment option in two cases of rectovaginal fistula discussed here. As described in this report, irradiated rectovaginal fistulas in rectal cancer patients were successfully treated with SVF injection, and we suggest SVF as a feasible treatment option for cases of rectovaginal fistula that would otherwise be very difficult to cure.
Files in This Item:
T202125973.pdf Download
DOI
10.5999/aps.2020.01718
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Plastic and Reconstructive Surgery (성형외과학교실) > 1. Journal Papers
Yonsei Authors
Roh, Tai Suk(노태석) ORCID logo https://orcid.org/0000-0001-8681-159X
Song, Seung Yong(송승용) ORCID logo https://orcid.org/0000-0002-3145-7463
Lew, Dae Hyun(유대현)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/190328
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