Consensus report from the 8th International Forum for Liver Magnetic Resonance Imaging
Authors
Christoph J Zech ; Ahmed Ba-Ssalamah ; Thomas Berg ; Hersh Chandarana ; Gar-Yang Chau ; Luigi Grazioli ; Myeong-Jin Kim ; Jeong Min Lee ; Elmar M Merkle ; Takamichi Murakami ; Jens Ricke ; Claude B Sirlin ; Bin Song ; Bachir Taouli ; Kengo Yoshimitsu ; Dow-Mu Koh
Gadoxetic acid ; Hepatocellular carcinoma ; Magnetic resonance imaging
Abstract
Objectives The 8th International Forum for Liver Magnetic Resonance Imaging (MRI), held in Basel, Switzerland, in October 2017, brought together clinical and academic radiologists from around the world to discuss developments in and reach consensus on key issues in the field of gadoxetic acid-enhanced liver MRI since the previous Forum held in 2013. Methods Two main themes in liver MRI were considered in detail at the Forum: the use of gadoxetic acid for contrast-enhanced MRI in patients with liver cirrhosis and the technical performance of gadoxetic acid-enhanced liver MRI, both opportunities and challenges. This article summarises the expert presentations and the delegate voting on consensus statements discussed at the Forum. Results and conclusions It was concluded that gadoxetic acid-enhanced MRI has higher sensitivity for the diagnosis of hepatocellular carcinoma (HCC), when compared with multidetector CT, by utilising features of hyperenhancement in the arterial phase and hypointensity in the hepatobiliary phase (HBP). Recent HCC management guidelines recognise an increasing role for gadoxetic acid-enhanced MRI in early diagnosis and monitoring post-resection. Additional research is needed to define the role of HBP in predicting microvascular invasion, to better define washout during the transitional phase in gadoxetic acid-enhanced MRI for HCC diagnosis, and to reduce the artefacts encountered in the arterial phase. Technical developments are being directed to shortening the MRI protocol for reducing time and patient discomfort and toward utilising faster imaging and non-Cartesian free-breathing approaches that have the potential to improve multiphasic dynamic imaging.