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Epidemiological characteristics of subsyndromal depression in late life

Authors
 Dae Jong Oh  ;  Ji Won Han  ;  Tae Hui Kim  ;  Kyung Phil Kwak  ;  Bong Jo Kim  ;  Shin Gyeom Kim  ;  Jeong Lan Kim  ;  Seok Woo Moon  ;  Joon Hyuk Park  ;  Seung-Ho Ryu  ;  Jong Chul Youn  ;  Dong Young Lee  ;  Dong Woo Lee  ;  Seok Bum Lee  ;  Jung Jae Lee  ;  Jin Hyeong Jhoo  ;  Ki Woong Kim 
Citation
 AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY, Vol.54(2) : 150-158, 2020-02 
Journal Title
AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY
ISSN
 0004-8674 
Issue Date
2020-02
MeSH
Aged ; Depressive Disorder / epidemiology* ; Depressive Disorder, Major / epidemiology* ; Female ; Humans ; Incidence ; Independent Living ; Late Onset Disorders / epidemiology* ; Male ; Middle Aged ; Prevalence ; Prodromal Symptoms* ; Prospective Studies ; Republic of Korea / epidemiology ; Risk Factors
Keywords
Depression ; geriatric psychiatry ; incidence ; risk factors ; epidemiology
Abstract
Objectives: Subsyndromal depression is prevalent and associated with poor outcomes in late life, but its epidemiological characteristics have barely been investigated. The aim of this prospective cohort study is to compare the prevalence, incidence and risk factors of subsyndromal depression with those of syndromal depression including major and minor depressive disorders in community-dwelling elderly individuals. Methods: In a nationwide community-based study of randomly sampled Korean elderly population aged 60 years or older (N = 6640), depression was assessed with standardized diagnostic interviews. At baseline and at 2-year and 4-year follow-ups, the authors diagnosed subsyndromal depression by the operational criteria and syndromal depression by the Diagnostic and Statistical Manual of Mental Disorders (4th ed.) diagnostic criteria. Multivariate logistic regression analyses were conducted to identify the risk factors for incident depression. Results: The age- and gender-adjusted prevalence rate of subsyndromal depression was 9.24% (95% confidence interval = [8.54, 9.93]), which was 2.4-fold higher than that of syndromal depression. The incidence rate of subsyndromal depression was 21.70 per 1000 person-years (95% confidence interval = [19.29, 24.12]), which was fivefold higher than that of syndromal depression. The prevalence to incidence ratio of subsyndromal depression was about half that of syndromal depression. The risk for subsyndromal depression was associated with female gender, low socioeconomic status, poor social support and poor sleep quality, while that of syndromal depression was associated with old age and less exercise. Conclusion: Subsyndromal depression should be validated as a clinical diagnostic entity, at least in late life, since it has epidemiological characteristics different from those of syndromal depression.
Full Text
https://journals.sagepub.com/doi/10.1177/0004867419879242
DOI
10.1177/0004867419879242
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실) > 1. Journal Papers
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/190259
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