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Safety and Efficacy of a Large-Bore Biliary Metallic Stent for Malignant Biliary Obstruction

 Min Young Do  ;  Sung Ill Jang  ;  Jae Hee Cho  ;  Yonsoo Kim  ;  In-Jung Kim  ;  Kwang-Hun Lee  ;  Seung-Moon Joo  ;  Dong Ki Lee 
 JOURNAL OF CLINICAL MEDICINE, Vol.11(11) : 3092, 2022-05 
Journal Title
Issue Date
dumbbell-shaped FCSEMS ; fully covered ; large-bore ; malignant biliary obstruction ; self-expandable metallic stent (FCSEMS)
Self-expandable metallic stents (SEMSs) are typically inserted in patients with unresectable malignant biliary obstruction. However, SEMSs are susceptible to occlusion. To overcome this issue, we developed a large-bore, dumbbell-shaped, fully covered SEMS (FCSEMS-L) and compared its efficacy and safety with those of a conventional FCSEMS (FCSEMS-C) in patients with malignant biliary obstruction.

Methods: Patients with unresectable distal malignant biliary obstruction were retrospectively enrolled between January 2011 and February 2021. All patients underwent endoscopic insertion of FCSEMSs. Recurrent biliary obstruction (RBO), patient survival time, complications, and prognosis were analyzed.

Results: RBO occurred in 31 patients (35.6%) who received an FCSEMS-L, and in 34 (45.9%) who received an FCSEMS-C. Stent occlusion occurred in 19 patients (21.8%) who received an FCSEMS-L, and in 22 (29.7%) who received an FCSEMS-C. Stent migration occurred in 12 patients (13.8%) with an FCSEMS-L and 12 (16.2%) with an FCSEMS-C. The median time to RBO (TRBO) was 301 days with an FCSEMS-L and 203 days with an FCSEMS-C. The median survival time was 479 days with an FCSEMS-L and 523 days with an FCSEMS-C. The TRBO and patient survival time did not significantly differ between the two groups.

Conclusions: There were no significant differences in efficacy and complication rates between the fully covered large bore SEMSs and conventional fully covered SEMSs.
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, In Joong(김인중)
Do, Min-Young(도민영)
Lee, Kwang Hun(이광훈)
Lee, Dong Ki(이동기) ORCID logo https://orcid.org/0000-0002-0048-9112
Jang, Sung Ill(장성일) ORCID logo https://orcid.org/0000-0003-4937-6167
Cho, Jae Hee(조재희) ORCID logo https://orcid.org/0000-0003-4174-0091
Joo, Seung Moon(주승문) ORCID logo https://orcid.org/0000-0002-0647-2880
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