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Semi-Quantitative Scoring of Late Gadolinium Enhancement of the Left Ventricle in Patients with Ischemic Cardiomyopathy: Improving Interobserver Reliability and Agreement Using Consensus Guidance from the Asian Society of Cardiovascular Imaging-Practical Tutorial (ASCI-PT) 2020

 Cherry Kim  ;  Chul Hwan Park  ;  Do Yeon Kim  ;  Jaehyung Cha  ;  Bae Young Lee  ;  Chan Ho Park  ;  Eun-Ju Kang  ;  Hyun Jung Koo  ;  Kakuya Kitagawa  ;  Min Jae Cha  ;  Rungroj Krittayaphong  ;  Sang Il Choi  ;  Sanjaya Viswamitra  ;  Sung Min Ko  ;  Sung Mok Kim  ;  Sung Ho Hwang  ;  Nguyen Ngoc Trang  ;  Whal Lee  ;  Young Jin Kim  ;  Jongmin Lee  ;  Dong Hyun Yang 
 KOREAN JOURNAL OF RADIOLOGY, Vol.23(3) : 298-307, 2022-03 
Journal Title
Issue Date
Cardiomyopathies* / diagnostic imaging ; Contrast Media ; Female ; Gadolinium ; Heart Ventricles ; Humans ; Magnetic Resonance Imaging, Cine / methods ; Male ; Middle Aged ; Myocardial Ischemia* / diagnostic imaging ; Reproducibility of Results
Consensus development ; Ischemic cardiomyopathy ; Late gadolinium enhancement ; Magnetic resonance imaging ; Myocardial viability
Objective: This study aimed to evaluate the effect of implementing the consensus statement from the Asian Society of Cardiovascular Imaging-Practical Tutorial 2020 (ASCI-PT 2020) on the reliability of cardiac MR with late gadolinium enhancement (CMR-LGE) myocardial viability scoring between observers in the context of ischemic cardiomyopathy.

Materials and methods: A total of 17 cardiovascular imaging experts from five different countries evaluated CMR obtained in 26 patients (male:female, 23:3; median age [interquartile range], 55.5 years [50-61.8]) with ischemic cardiomyopathy. For LGE scoring, based on the 17 segments, the extent of LGE in each segment was graded using a five-point scoring system ranging from 0 to 4 before and after exposure according to the consensus statement. All scoring was performed via web-based review. Scores for slices, vascular territories, and total scores were obtained as the sum of the relevant segmental scores. Interobserver reliability for segment scores was assessed using Fleiss' kappa, while the intraclass correlation coefficient (ICC) was used for slice score, vascular territory score, and total score. Inter-observer agreement was assessed using the limits of agreement from the mean (LoA).

Results: Interobserver reliability (Fleiss' kappa) in each segment ranged 0.242-0.662 before the consensus and increased to 0.301-0.774 after the consensus. The interobserver reliability (ICC) for each slice, each vascular territory, and total score increased after the consensus (slice, 0.728-0.805 and 0.849-0.884; vascular territory, 0.756-0.902 and 0.852-0.941; total score, 0.847 and 0.913, before and after implementing the consensus statement, respectively. Interobserver agreement in scoring also improved with the implementation of the consensus for all slices, vascular territories, and total score. The LoA for the total score narrowed from ± 10.36 points to ± 7.12 points.

Conclusion: The interobserver reliability and agreement for CMR-LGE scoring for ischemic cardiomyopathy improved when following guidance from the ASCI-PT 2020 consensus statement.
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1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Young Jin(김영진) ORCID logo https://orcid.org/0000-0002-6235-6550
Park, Chul Hwan(박철환) ORCID logo https://orcid.org/0000-0002-0004-9475
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