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A prospective comparative study of radiotherapy effect upon scar quality

Authors
 Seung Jin Moon  ;  Il Hwan Byun  ;  Jee Suk Chang  ;  Seung Yong Song  ;  Won Jai Lee  ;  Dong Won Lee 
Citation
 JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY, Vol.74(8) : 1801-1806, 2021-08 
Journal Title
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
ISSN
 1748-6815 
Issue Date
2021-08
MeSH
Adult ; Breast Neoplasms / surgery* ; Cicatrix / radiotherapy* ; Female ; Humans ; Mammaplasty ; Mastectomy ; Middle Aged ; Postoperative Complications / radiotherapy* ; Prospective Studies
Keywords
Oncoplastic reduction ; Postoperative scar ; Radiation ; Surgery
Abstract
Introduction: The effect of radiation on uncomplicated postoperative scars is unclear. This study aimed to analyze irradiated and non-irradiated scars in patients with unilateral breast cancer, who underwent oncoplastic breast reduction surgery and radiation therapy (RT), to identify how postoperative scar changes with radiation.

Methods: Twenty breast scars in 10 patients were analyzed after unilateral breast-conserving surgery, oncoplastic breast reduction, and RT. Scars were assessed using the Vancouver scar scale (VSS) by two independent blinded observers and three-dimensional scar analysis camera. Paired t-test between irradiated and non-irradiated scars in each patient and correlation of scar score differences with potential contributing factors were analyzed.

Results: The VSS was significantly lower for the irradiated scar than that for the non-irradiated contralateral scar (1.40 vs. 4.05, p = 0.001), although time interval from the last radiation to scar assessment had a negative correlation with paired differences of VSS (Spearman's correlation coefficient: -0.637, p = 0.048). Compared with the non-irradiated scar, the irradiated scar showed a significantly high level of hemoglobin (1.04 vs. 1.26, p = 0.017) and melanin (0.55 vs. 0.63, p = 0.03).

Conclusions: Postoperative scars with radiation showed better results in objective and subjective assessments than scars without radiation. These findings suggest that radiation has a positive effect on general scar maturation.
Full Text
https://www.sciencedirect.com/science/article/pii/S1748681520306641
DOI
10.1016/j.bjps.2020.11.044
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Plastic and Reconstructive Surgery (성형외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers
Yonsei Authors
Byun, Il Hwan(변일환)
Song, Seung Yong(송승용) ORCID logo https://orcid.org/0000-0002-3145-7463
Lee, Dong Won(이동원) ORCID logo https://orcid.org/0000-0003-0046-3139
Lee, Won Jai(이원재) ORCID logo https://orcid.org/0000-0003-3056-0503
Chang, Jee Suk(장지석) ORCID logo https://orcid.org/0000-0001-7685-3382
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/187108
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