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A prospective comparative study of radiotherapy effect upon scar quality

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dc.contributor.author변일환-
dc.contributor.author송승용-
dc.contributor.author이동원-
dc.contributor.author이원재-
dc.contributor.author장지석-
dc.date.accessioned2021-12-28T17:27:18Z-
dc.date.available2021-12-28T17:27:18Z-
dc.date.issued2021-08-
dc.identifier.issn1748-6815-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/187108-
dc.description.abstractIntroduction: The effect of radiation on uncomplicated postoperative scars is unclear. This study aimed to analyze irradiated and non-irradiated scars in patients with unilateral breast cancer, who underwent oncoplastic breast reduction surgery and radiation therapy (RT), to identify how postoperative scar changes with radiation. Methods: Twenty breast scars in 10 patients were analyzed after unilateral breast-conserving surgery, oncoplastic breast reduction, and RT. Scars were assessed using the Vancouver scar scale (VSS) by two independent blinded observers and three-dimensional scar analysis camera. Paired t-test between irradiated and non-irradiated scars in each patient and correlation of scar score differences with potential contributing factors were analyzed. Results: The VSS was significantly lower for the irradiated scar than that for the non-irradiated contralateral scar (1.40 vs. 4.05, p = 0.001), although time interval from the last radiation to scar assessment had a negative correlation with paired differences of VSS (Spearman's correlation coefficient: -0.637, p = 0.048). Compared with the non-irradiated scar, the irradiated scar showed a significantly high level of hemoglobin (1.04 vs. 1.26, p = 0.017) and melanin (0.55 vs. 0.63, p = 0.03). Conclusions: Postoperative scars with radiation showed better results in objective and subjective assessments than scars without radiation. These findings suggest that radiation has a positive effect on general scar maturation.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherElsevier-
dc.relation.isPartOfJOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHAdult-
dc.subject.MESHBreast Neoplasms / surgery*-
dc.subject.MESHCicatrix / radiotherapy*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMammaplasty-
dc.subject.MESHMastectomy-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPostoperative Complications / radiotherapy*-
dc.subject.MESHProspective Studies-
dc.titleA prospective comparative study of radiotherapy effect upon scar quality-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Plastic and Reconstructive Surgery (성형외과학교실)-
dc.contributor.googleauthorSeung Jin Moon-
dc.contributor.googleauthorIl Hwan Byun-
dc.contributor.googleauthorJee Suk Chang-
dc.contributor.googleauthorSeung Yong Song-
dc.contributor.googleauthorWon Jai Lee-
dc.contributor.googleauthorDong Won Lee-
dc.identifier.doi10.1016/j.bjps.2020.11.044-
dc.contributor.localIdA04954-
dc.contributor.localIdA02032-
dc.contributor.localIdA02729-
dc.contributor.localIdA03005-
dc.contributor.localIdA04658-
dc.relation.journalcodeJ01714-
dc.identifier.eissn1878-0539-
dc.identifier.pmid33358674-
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S1748681520306641-
dc.subject.keywordOncoplastic reduction-
dc.subject.keywordPostoperative scar-
dc.subject.keywordRadiation-
dc.subject.keywordSurgery-
dc.contributor.alternativeNameByun, Il Hwan-
dc.contributor.affiliatedAuthor변일환-
dc.contributor.affiliatedAuthor송승용-
dc.contributor.affiliatedAuthor이동원-
dc.contributor.affiliatedAuthor이원재-
dc.contributor.affiliatedAuthor장지석-
dc.citation.volume74-
dc.citation.number8-
dc.citation.startPage1801-
dc.citation.endPage1806-
dc.identifier.bibliographicCitationJOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY, Vol.74(8) : 1801-1806, 2021-08-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Plastic and Reconstructive Surgery (성형외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers

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