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Treatment Response Evaluation of Cardiac Amyloidosis Using Serial T1- and T2-Mapping Cardiovascular Magnetic Resonance Imaging

Other Titles
 T1 지도화 기법 심장 자기공명영상 추적 검사를 이용한 심장 아밀로이드증의 치료 반응 평가 
Authors
 Jinwoo Son  ;  Yoo Jin Hong 
Citation
 Journal of the Korean Society of Radiology (대한영상의학회지), Vol.82(2) : 429-434, 2021-03 
Journal Title
Journal of the Korean Society of Radiology(대한영상의학회지)
ISSN
 1738-2637 
Issue Date
2021-03
Keywords
Amyloidosis, Cardiac ; Extracellular Matrix ; Magnetic Resonance Imaging
Abstract
Amyloidosis is a multisystemic disease characterized by the accumulation of abnormal proteins in extracellular spaces in various organs, with frequent involvement of the myocardium. We report a case of a patient who had cardiac amyloidosis with a trend of reduction in native T1 and T2 values and extracellular volume fraction on serial cardiac magnetic resonance imaging after chemotherapy and stem cell transplantation. The native T1 value and the extracellular volume fraction are closely associated with tissue amyloid burden in amyloidosis patients. This case demonstrated that cardiac magnetic resonance imaging may be used as a non-invasive and quantitative biomarker in the treatment monitoring of amyloidosis.
Files in This Item:
T202104994.pdf Download
DOI
10.3348/jksr.2020.0048
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Hong, Yoo Jin(홍유진) ORCID logo https://orcid.org/0000-0002-7276-0944
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/187061
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