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Effect of intraoperative fluid volume on postoperative ileus after robot-assisted radical cystectomy

 Ji Sung Shim  ;  Tae Il Noh  ;  Ja Hyeon Ku  ;  Sangchul Lee  ;  Tae Gyun Kwon  ;  Tae-Hwan Kim  ;  Seung Hyun Jeon  ;  Sang Hyup Lee  ;  Jong Kil Nam  ;  Wan Seok Kim  ;  Byong Chang Jeong  ;  Ji Youl Lee  ;  Sung Hoo Hong  ;  Koon Ho Rha  ;  Woong Kyu Han  ;  Won Sik Ham  ;  Young Goo Lee  ;  Yong Seong Lee  ;  Sung Yul Park  ;  Young Eun Yoon  ;  Sung Gu Kang  ;  Jong Jin Oh  ;  Seok Ho Kang 
 SCIENTIFIC REPORTS, Vol.11(1) : 10522, 2021-05 
Journal Title
Issue Date
Aged ; Body Fluids* ; Cystectomy / adverse effects* ; Female ; Humans ; Ileus / etiology* ; Intraoperative Period ; Length of Stay ; Male ; Middle Aged ; Postoperative Complications / etiology* ; Retrospective Studies ; Robotic Surgical Procedures / adverse effects* ; Treatment Outcome
This study aimed to investigate the effect of intraoperative fluid volume on the postoperative ileus (POI) recovery period. A retrospective review of the Korean robot-assisted radical cystectomy database identified 718 patients who underwent robot-assisted radical cystectomy (RARC). Regression analyses were performed to identify the associations between the amount of intraoperative fluid administration (crystalloid/colloid/total), POI period (time to flatus/bowel movements), and length of hospital stay (LOS) after adjusting for covariates. In addition, we analyzed the risk factors for gastrointestinal complications and prolonged POI using a logistic regression model. An increasing volume of the administered crystalloid/total fluid was associated with prolonged POI (crystalloid R2 = 0.0725 and P < 0.0001; total amount R2 = 0.0812 and P < 0.0001), and the total fluid volume was positively associated with the LOS (R2 = 0.099 and P < 0.0001). The crystalloid amount was a risk factor for prolonged POI (P < 0.001; odds ratio, 1.361; 95% confidence interval, 1.133-1.641; P < 0.001). In the context of RARC, increased intravenous fluids are associated with prolonged POI and longer LOS.
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1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers
Yonsei Authors
Rha, Koon Ho(나군호) ORCID logo https://orcid.org/0000-0001-8588-7584
Han, Woong Kyu(한웅규) ORCID logo https://orcid.org/0000-0002-2527-4046
Ham, Won Sik(함원식) ORCID logo https://orcid.org/0000-0003-2246-8838
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