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Disordered Nanocomposite Islands for Nanospeckle Illumination Microscopy in Wide-Field Super-Resolution Imaging

Authors
 Hajun Yoo  ;  Hongki Lee  ;  Woo Joong Rhee  ;  Gwiyeong Moon  ;  Changhun Lee  ;  Seung Ah Lee  ;  Jeon-Soo Shin  ;  Donghyun Kim 
Citation
 ADVANCED OPTICAL MATERIALS, Vol.9(15) : 2100211, 2021-08 
Journal Title
ADVANCED OPTICAL MATERIALS
ISSN
 2195-1071 
Issue Date
2021-08
Abstract
Nanospeckle illumination microscopy (NanoSIM) based on disordered metallic nanocomposite island substrates is described. The nanoisland substrates can be fabricated without lithographic techniques. Azimuthal scanning illumination of nanoislands creates near-field distribution that excites an arbitrary number of basis images to produce super-resolution. Experimental studies of point-spread images using NanoSIM with 360 basis images obtained by azimuthal scanning find spatial resolution improved by more than three times with an achievable full-width-at-half-maximum at 81.1 nm on average. The approach is confirmed by imaging aggregated nanobeads and nanoscale distribution of gangliosides on the HeLa cell membrane.
Full Text
https://onlinelibrary.wiley.com/doi/full/10.1002/adom.202100211
DOI
10.1002/adom.202100211
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Microbiology (미생물학교실) > 1. Journal Papers
Yonsei Authors
Shin, Jeon Soo(신전수) ORCID logo https://orcid.org/0000-0002-8294-3234
Rhee, Woo Joong(이우중) ORCID logo https://orcid.org/0000-0001-9690-0553
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/184673
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