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Cited 4 times in

Comorbidity index for predicting mortality at 6 months after reperfusion therapy

DC Field Value Language
dc.contributor.author김동준-
dc.contributor.author김병문-
dc.contributor.author김영대-
dc.contributor.author김진권-
dc.contributor.author김현창-
dc.contributor.author남효석-
dc.contributor.author박형종-
dc.contributor.author유준상-
dc.contributor.author이경열-
dc.contributor.author이혜선-
dc.contributor.author정요한-
dc.contributor.author허준녕-
dc.contributor.author허지회-
dc.date.accessioned2021-04-29T17:21:31Z-
dc.date.available2021-04-29T17:21:31Z-
dc.date.issued2021-03-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/182303-
dc.description.abstractThe eligibility of reperfusion therapy has been expanded to increase the number of patients. However, it remains unclear the reperfusion therapy will be beneficial in stroke patients with various comorbidities. We developed a reperfusion comorbidity index for predicting 6-month mortality in patients with acute stroke receiving reperfusion therapy. The 19 comorbidities included in the Charlson comorbidity index were adopted and modified. We developed a statistical model and it was validated using data from a prospective cohort. Among 1026 patients in the retrospective nationwide reperfusion therapy registry, 845 (82.3%) had at least one comorbidity. As the number of comorbidities increased, the likelihood of mortality within 6 months also increased (p < 0.001). Six out of the 19 comorbidities were included for developing the reperfusion comorbidity index on the basis of the odds ratios in the multivariate logistic regression analysis. This index showed good prediction of 6-month mortality in the retrospective cohort (area under the curve [AUC], 0.747; 95% CI, 0.704-0.790) and in 333 patients in the prospective cohort (AUC, 0.784; 95% CI, 0.709-0.859). Consideration of comorbidities might be helpful for the prediction of the 6-month mortality in patients with acute ischemic stroke who receive reperfusion therapy.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageEnglish-
dc.publisherNature Publishing Group-
dc.relation.isPartOfSCIENTIFIC REPORTS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleComorbidity index for predicting mortality at 6 months after reperfusion therapy-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiology (영상의학교실)-
dc.contributor.googleauthorHyo Suk Nam-
dc.contributor.googleauthorYoung Dae Kim-
dc.contributor.googleauthorJoonsang Yoo-
dc.contributor.googleauthorHyungjong Park-
dc.contributor.googleauthorByung Moon Kim-
dc.contributor.googleauthorOh Young Bang-
dc.contributor.googleauthorHyeon Chang Kim-
dc.contributor.googleauthorEuna Han-
dc.contributor.googleauthorDong Joon Kim-
dc.contributor.googleauthorJoonyung Heo-
dc.contributor.googleauthorMinyoung Kim-
dc.contributor.googleauthorJin Kyo Choi-
dc.contributor.googleauthorKyung-Yul Lee-
dc.contributor.googleauthorHye Sun Lee-
dc.contributor.googleauthorDong Hoon Shin-
dc.contributor.googleauthorHye-Yeon Choi-
dc.contributor.googleauthorSung-Il Sohn-
dc.contributor.googleauthorJeong-Ho Hong-
dc.contributor.googleauthorJong Yun Lee-
dc.contributor.googleauthorJang-Hyun Baek-
dc.contributor.googleauthorGyu Sik Kim-
dc.contributor.googleauthorWoo-Keun Seo-
dc.contributor.googleauthorJong-Won Chung-
dc.contributor.googleauthorSeo Hyun Kim-
dc.contributor.googleauthorTae-Jin Song-
dc.contributor.googleauthorSang Won Han-
dc.contributor.googleauthorJoong Hyun Park-
dc.contributor.googleauthorJinkwon Kim-
dc.contributor.googleauthorYo Han Jung-
dc.contributor.googleauthorHan-Jin Cho-
dc.contributor.googleauthorSeong Hwan Ahn-
dc.contributor.googleauthorSung Ik Lee-
dc.contributor.googleauthorKwon-Duk Seo-
dc.contributor.googleauthorJi Hoe Heo-
dc.identifier.doi10.1038/s41598-021-85390-4-
dc.contributor.localIdA00410-
dc.contributor.localIdA00498-
dc.contributor.localIdA00702-
dc.contributor.localIdA01012-
dc.contributor.localIdA01142-
dc.contributor.localIdA01273-
dc.contributor.localIdA05600-
dc.contributor.localIdA02513-
dc.contributor.localIdA02648-
dc.contributor.localIdA03312-
dc.contributor.localIdA03659-
dc.contributor.localIdA06115-
dc.contributor.localIdA04369-
dc.relation.journalcodeJ02646-
dc.identifier.eissn2045-2322-
dc.identifier.pmid33727593-
dc.contributor.alternativeNameKim, Dong Joon-
dc.contributor.affiliatedAuthor김동준-
dc.contributor.affiliatedAuthor김병문-
dc.contributor.affiliatedAuthor김영대-
dc.contributor.affiliatedAuthor김진권-
dc.contributor.affiliatedAuthor김현창-
dc.contributor.affiliatedAuthor남효석-
dc.contributor.affiliatedAuthor박형종-
dc.contributor.affiliatedAuthor유준상-
dc.contributor.affiliatedAuthor이경열-
dc.contributor.affiliatedAuthor이혜선-
dc.contributor.affiliatedAuthor정요한-
dc.contributor.affiliatedAuthor허준녕-
dc.contributor.affiliatedAuthor허지회-
dc.citation.volume11-
dc.citation.number1-
dc.citation.startPage5963-
dc.identifier.bibliographicCitationSCIENTIFIC REPORTS, Vol.11(1) : 5963, 2021-03-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Preventive Medicine (예방의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers

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