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폐암의 바이오마커와 진단도구

Other Titles
 Biomarkers and diagnostic tools for lung cancer 
Authors
 이상훈  ;  이은혜  ;  김은영  ;  최용준  ;  차윤진  ;  장윤수 
Citation
 JOURNAL OF THE KOREAN MEDICAL ASSOCIATION, Vol.64(1) : 66-74, 2021-01 
Journal Title
JOURNAL OF THE KOREAN MEDICAL ASSOCIATION (대한의사협회지)
ISSN
 1975-8456 
Issue Date
2021-01
Keywords
Lung neoplasms ; Screening ; Diagnosis ; Biomarkers ; Liquid biopsy
Abstract
Lung cancer is the leading cause of cancer-related deaths in developing to advanced countries worldwide. The incidence rate of lung cancer in Korea has been increasing steadily since 1997. Statistics show that in 2017 alone, the incidence and mortality rates for lung cancer were 52.7 and 34.8 per 100,000 people, respectively, accounting for the highest cause of cancer death in Korea. The process of accurately diagnosing lung cancer consists of several steps, starting with the discovery of pulmonary nodule(s) via a cancer screening test or various other methods followed by the collection of cells or tissues and the identification of target molecules. Thereafter, staging and the development of a therapeutic plan lead to improved clinical outcomes. After the completion of a pilot study, a nationwide lung cancer screening program was introduced in Korea; since 2019, this program has targeted population at high risk for lung cancer: men and women aged 54 to 74 years who had a smoking history of 30 pack-years or more. The frequency of detection of pulmonary nodules is increasing in proportion to the public interest in health and economic growth. In this review, we present diagnostic techniques and biomarkers that are widely used in the medical field in the hope that such information would benefit clinical practice.
Files in This Item:
T202100272.pdf Download
DOI
10.5124/jkma.2021.64.1.66
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
Yonsei Authors
Kim, Eun Young(김은영) ORCID logo https://orcid.org/0000-0002-3281-5744
Lee, Sang Hoon(이상훈B) ORCID logo https://orcid.org/0000-0002-3619-4340
Lee, Eun Hye(이은혜) ORCID logo https://orcid.org/0000-0003-2570-3442
Chang, Yoon Soo(장윤수) ORCID logo https://orcid.org/0000-0003-3340-4223
Cha, Yoon Jin(차윤진) ORCID logo https://orcid.org/0000-0002-5967-4064
Choi, Yong Jun(최용준) ORCID logo https://orcid.org/0000-0002-6114-2059
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/182040
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