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Commissioning and clinical implementation of Mobius3D and MobiusFX: Experience on multiple linear accelerators

Authors
 Jihun Kim  ;  Min Cheol Han  ;  Kwangwoo Park  ;  Kyung Hwan Chang  ;  Dong Wook Kim  ;  Chae-Seon Hong  ;  Jin Sung Kim 
Citation
 PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS, Vol.80 : 1-9, 2020-12 
Journal Title
 PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS 
ISSN
 1120-1797 
Issue Date
2020-12
Keywords
Clinical implementation ; Commissioning ; Mobius3D ; Patient-specific quality assurance ; Volumetric-modulated arc therapy
Abstract
Purpose: To provide practical guidelines for Mobius3D commissioning based on experiences of commissioning/clinical implementation of Mobius3D and MobiusFX as patient-specific quality assurance tools on multiple linear accelerators. Methods: The vendor-suggested Mobius3D commissioning procedures, including beam model adjustment and dosimetric leaf gap (DLG) optimization, were performed for 6 MV X-ray beams of six Elekta linear accelerators. For the beam model adjustment, beam data, such as the percentage depth dose, off-axis ratio (OAR), and output factor (OF), were measured using a water phantom and compared to the vendor-provided reference values. DLG optimization was performed to determine an optimal DLG correction factor to minimize the mean difference between Mobius3D-calculated and measured doses for multiple volumetric modulated arc therapy (VMAT) plans. Small-field VMAT plans, in which Mobius3D has dose calculate uncertainties, were initially included in the DLG optimization, but excluded later. Results: The measured beam data were consistent across the six linear accelerators. Relatively large differences between the reference and measured values were observed for the OAR at large off-axis distances (>5 cm) and for the OF for small fields (<3 × 3 cm2). The optimal DLG correction factor was 0.6 ± 0.3 (range: 0.3-1.0) with small-field plans and 0.2 ± 0.2 (0.0-0.5) without them. Conclusions: A reasonable agreement was found between the vendor-provided reference and measured beam models. DLG optimization results were dependent on the selection of the VMAT plans, requiring careful attention to the known dose calculation uncertainties of Mobius3D when determining a DLG correction factor.
Full Text
https://www.sciencedirect.com/science/article/pii/S1120179720302441
DOI
10.1016/j.ejmp.2020.10.004
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers
Yonsei Authors
Kim, Dong Wook(김동욱) ORCID logo https://orcid.org/0000-0002-5819-9783
Kim, Jihun(김지훈) ORCID logo https://orcid.org/0000-0003-4856-6305
Kim, Jinsung(김진성) ORCID logo https://orcid.org/0000-0003-1415-6471
Park, Kwang Woo(박광우) ORCID logo https://orcid.org/0000-0002-9843-7985
Chang, Kyung Hwan(장경환)
Han, Min Cheol(한민철)
Hong, Chae-Seon(홍채선) ORCID logo https://orcid.org/0000-0001-9120-6132
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/180662
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