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Shape Memory Tube Plug for Fine-control of Intraocular Pressure by Glaucoma Devices

Authors
 Won Taek Oh  ;  Jung Bok Lee  ;  Wungrak Choi  ;  Hyoung Won Bae  ;  Chang Soo Kim  ;  Chan Yun Kim  ;  Hak-Joon Sung 
Citation
 ACS BIOMATERIALS SCIENCE & ENGINEERING, Vol.6(7) : 3784-3790, 2020-07 
Journal Title
 ACS BIOMATERIALS SCIENCE & ENGINEERING 
Issue Date
2020-07
Keywords
glaucoma ; shape memory ; self-diameter expansion ; tube insertion ; intraocular pressure
Abstract
As a standard approach to treating glaucoma, a silicone tube device is inserted into the eye to drain water and thereby lower the intraocular pressure (IOP). However, the fixed diameter of the tube often results in too much initial water drain. Suture-sheaving of the outer tube wall also leads to random IOP drops over time. In this study, self-expansion of the inner tube diameter was achieved by inserting a shape memory tube into the silicone tube. The difference in controlling small to large IOP drops before and after tube diameter expansion was demonstrated via computational modeling, a flow pumping system, and rabbit experiments.
Full Text
https://pubs.acs.org/doi/abs/10.1021/acsbiomaterials.0c00649
DOI
10.1021/acsbiomaterials.0c00649
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Medical Engineering (의학공학교실) > 1. Journal Papers
Yonsei Authors
Kim, Chan Yun(김찬윤) ORCID logo https://orcid.org/0000-0002-8373-9999
Bae, Hyoung Won(배형원) ORCID logo https://orcid.org/0000-0002-8421-5636
Sung, Hak-Joon(성학준) ORCID logo https://orcid.org/0000-0003-2312-2484
Choi, Wungrak(최웅락) ORCID logo https://orcid.org/0000-0002-3015-2502
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/180388
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