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조영증강 경사에코 Echo Planar Imaging을 이용한 대뇌 혈액량 및 상대적 관류도 영상

Other Titles
 Cerebral Blood Volume and Relative Perfusion Rate Mapping with Contrast Enhanced Gradient Echo Echo Planar Imaging 
 이승구  ;  김동익  ;  정은기  ;  허용민  ;  황금주  ;  전평  ;  윤평호  ;  김현숙 
 Journal of the Korean Radiologist Society (대한방사선의학회지), Vol.39(2) : 249-255, 1998 
Journal Title
 Journal of the Korean Radiologist Society (대한방사선의학회지) 
Issue Date
MR, image processing ; MR, vascular studies ; Brain, blood flow
PURPOSE: To assess regional cerebral blood volume and perfusion rate by MR imaging. MATERIALS AND METHODS:Eight normal volunteers and one patient underwent MR imaging after bolus injection of a double dose ofgadoinium(0.2mMol/kg). Gradient-echo EPI pulse sequencing was used, with TR/TE 1500/40msec, flip angle 90o, matrixsize 256X128. One hundred sequential images at the same level were obtained. The time-signal intensity curve wasplotted and converted to a time-concentration ( R2) curve. Relative cerebral blood volume was determined, withintegration of time-concentration curve pixel by pixel. Perfusion rate was determined by calculating maximal slopeof the R2 curve and the time taken to attain this. RESULTS: On volume maps, clear differentiation of gray matter,white matter and major vessels was established. The mean gray and white matter ratio of blood volume was2.78+/-0.43. Slope and volume maps were similar, but in one patient perfusion was apparently greater on the ratemap than on the volume map. CONCLUSION: Cerebral blood volvme and slope map images reflect changes in cerebralhemodynamics. It is thought that these findings can be clinically applied to the determination of vascularity inbrain tumors and acute cerebral ischemia
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1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Dong Ik(김동익)
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