0 42

Cited 0 times in

45세 이상 한국 남성에서 혈청 테스토스테론, 성호르몬결합글로불린 농도와 대사증후군의 관련성

Other Titles
 Association between serum testosterone and sex hormone binding globulin levels and metabolic syndrome in Korean men aged 45 years and older 
Authors
 윤은경  ;  이용제 
Citation
 Journal of Korean Institute for Functional Medicine, Vol.3(1) : 9-14, 2020-06 
Journal Title
 Journal of Korean Institute for Functional Medicine 
Issue Date
2020-06
Keywords
Testosterone ; Sex hormone-binding globulin ; Metabolic syndrome
Abstract
Background: This study aimed to investigate relationship between serum testosterone and sex hormone binding globulin (SHBG) levels and metabolic syndrome in Korean men aged ≥45 years old. Methods: This cross-sectional study included a total of 1,121 individuals who underwent health check-ups between November 2007 and July 2010 at the Health Promotion Center of Gangnam Severance Hospital in Seoul. Serum testosterone and SHGB levels were categorized into quartiles: Q1: ≤12.2, Q2: 12.3-15.7, Q3: 15.8-19.6, and Q4: ≥19.7 nmol/L for testosterone and Q1: ≤29.7, Q2: 29.8-39.1, Q3: 39.2-50.8, and Q4: ≥50.9 nmol/L for SHBG levels. The odds ratios and 95% confidence intervals for metabolic syndrome were calculated using multiple logistic regression analysis after adjusting for confounding factors across serum testosterone and SHGB quartiles. Results: The prevalence of metabolic syndrome gradually increased with decreasing quartiles of testosterone and SHBG levels. Compared with the highest quartile, the odds ratio the lowest quartile was 3.37 (2.21-5.13) for testosterone and 4.72 (3.02-7.38) for SHBG after adjusting for age, cigarette smoking, alcohol intake, regular exercise, hepatic enzymes, and leukocyte count. Conclusion: Serum testosterone and SHGB levels was inversely associated with metabolic syndrome in middle aged and elderly Korean males in a dose-response manner.
Full Text
http://scholar.dkyobobook.co.kr/searchDetail.laf?barcode=4010027717562
DOI
10.32581/jkifm.2020.3.1.9
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Family Medicine (가정의학교실) > 1. Journal Papers
Yonsei Authors
Lee, Yong Jae(이용제) ORCID logo https://orcid.org/0000-0002-6697-476X
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/176212
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links