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45세 이상 한국 남성에서 혈청 테스토스테론, 성호르몬결합글로불린 농도와 대사증후군의 관련성
DC Field | Value | Language |
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dc.contributor.author | 이용제 | - |
dc.date.accessioned | 2020-06-17T01:00:09Z | - |
dc.date.available | 2020-06-17T01:00:09Z | - |
dc.date.issued | 2020-06 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/176212 | - |
dc.description.abstract | Background: This study aimed to investigate relationship between serum testosterone and sex hormone binding globulin (SHBG) levels and metabolic syndrome in Korean men aged ≥45 years old. Methods: This cross-sectional study included a total of 1,121 individuals who underwent health check-ups between November 2007 and July 2010 at the Health Promotion Center of Gangnam Severance Hospital in Seoul. Serum testosterone and SHGB levels were categorized into quartiles: Q1: ≤12.2, Q2: 12.3-15.7, Q3: 15.8-19.6, and Q4: ≥19.7 nmol/L for testosterone and Q1: ≤29.7, Q2: 29.8-39.1, Q3: 39.2-50.8, and Q4: ≥50.9 nmol/L for SHBG levels. The odds ratios and 95% confidence intervals for metabolic syndrome were calculated using multiple logistic regression analysis after adjusting for confounding factors across serum testosterone and SHGB quartiles. Results: The prevalence of metabolic syndrome gradually increased with decreasing quartiles of testosterone and SHBG levels. Compared with the highest quartile, the odds ratio the lowest quartile was 3.37 (2.21-5.13) for testosterone and 4.72 (3.02-7.38) for SHBG after adjusting for age, cigarette smoking, alcohol intake, regular exercise, hepatic enzymes, and leukocyte count. Conclusion: Serum testosterone and SHGB levels was inversely associated with metabolic syndrome in middle aged and elderly Korean males in a dose-response manner. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | Korean | - |
dc.publisher | 대한기능의학회 | - |
dc.relation.isPartOf | Journal of Korean Institute for Functional Medicine | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | 45세 이상 한국 남성에서 혈청 테스토스테론, 성호르몬결합글로불린 농도와 대사증후군의 관련성 | - |
dc.title.alternative | Association between serum testosterone and sex hormone binding globulin levels and metabolic syndrome in Korean men aged 45 years and older | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Family Medicine (가정의학교실) | - |
dc.contributor.googleauthor | 윤은경 | - |
dc.contributor.googleauthor | 이용제 | - |
dc.identifier.doi | 10.32581/jkifm.2020.3.1.9 | - |
dc.contributor.localId | A02982 | - |
dc.relation.journalcode | J03471 | - |
dc.identifier.url | http://scholar.dkyobobook.co.kr/searchDetail.laf?barcode=4010027717562 | - |
dc.subject.keyword | Testosterone | - |
dc.subject.keyword | Sex hormone-binding globulin | - |
dc.subject.keyword | Metabolic syndrome | - |
dc.contributor.alternativeName | Lee, Yong Jae | - |
dc.contributor.affiliatedAuthor | 이용제 | - |
dc.citation.volume | 3 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 9 | - |
dc.citation.endPage | 14 | - |
dc.identifier.bibliographicCitation | Journal of Korean Institute for Functional Medicine, Vol.3(1) : 9-14, 2020-06 | - |
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