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Improving the Clinical Outcome in Stroke Patients Receiving Thrombolytic or Endovascular Treatment in Korea: From the SECRET Study

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dc.contributor.author김동준-
dc.contributor.author김병문-
dc.contributor.author김영대-
dc.contributor.author김진권-
dc.contributor.author김현창-
dc.contributor.author남효석-
dc.contributor.author박형종-
dc.contributor.author유준상-
dc.contributor.author이경열-
dc.contributor.author이혜선-
dc.contributor.author허지회-
dc.date.accessioned2020-06-17T00:53:21Z-
dc.date.available2020-06-17T00:53:21Z-
dc.date.issued2020-03-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/176169-
dc.description.abstractWe investigated whether there was an annual change in outcomes in patients who received the thrombolytic therapy or endovascular treatment (EVT) in Korea. This analysis was performed using data from a nationwide multicenter registry for exploring the selection criteria of patients who would benefit from reperfusion therapies in Korea. We compared the annual changes in the modified Rankin scale (mRS) at discharge and after 90 days and the achievement of successful recanalization from 2012 to 2017. We also investigated the determinants of favorable functional outcomes. Among 1230 included patients, the improvement of functional outcome at discharge after reperfusion therapy was noted as the calendar year increased (p < 0.001). The proportion of patients who were discharged to home significantly increased (from 45.6% in 2012 to 58.5% in 2017) (p < 0.001). The successful recanalization rate increased over time from 78.6% in 2012 to 85.1% in 2017 (p = 0.006). Time from door to initiation of reperfusion therapy decreased over the years (p < 0.05). These secular trends of improvements were also observed in 1203 patients with available mRS data at 90 days (p < 0.05). Functional outcome was associated with the calendar year, age, initial stroke severity, diabetes, preadmission disability, intervals from door to reperfusion therapy, and achievement of successful recanalization. This study demonstrated the secular trends of improvement in functional outcome and successful recanalization rate in patients who received reperfusion therapy in Korea.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherMDPI AG-
dc.relation.isPartOfJOURNAL OF CLINICAL MEDICINE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleImproving the Clinical Outcome in Stroke Patients Receiving Thrombolytic or Endovascular Treatment in Korea: From the SECRET Study-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiology (영상의학교실)-
dc.contributor.googleauthorYoung Dae Kim-
dc.contributor.googleauthorJi Hoe Heo-
dc.contributor.googleauthorJoonsang Yoo-
dc.contributor.googleauthorHyungjong Park-
dc.contributor.googleauthorByung Moon Kim-
dc.contributor.googleauthorOh Young Bang-
dc.contributor.googleauthorHyeon Chang Kim-
dc.contributor.googleauthorEuna Han-
dc.contributor.googleauthorDong Joon Kim-
dc.contributor.googleauthorJoonNyung Heo-
dc.contributor.googleauthorMinyoung Kim-
dc.contributor.googleauthorJin Kyo Choi-
dc.contributor.googleauthorKyung-Yul Lee-
dc.contributor.googleauthorHye Sun Lee-
dc.contributor.googleauthorDong Hoon Shin-
dc.contributor.googleauthorHye-Yeon Choi-
dc.contributor.googleauthorSung-Il Sohn-
dc.contributor.googleauthorJeong-Ho Hong-
dc.contributor.googleauthorJang-Hyun Baek-
dc.contributor.googleauthorGyu Sik Kim-
dc.contributor.googleauthorWoo-Keun Seo-
dc.contributor.googleauthorJong-Won Chung-
dc.contributor.googleauthorSeo Hyun Kim-
dc.contributor.googleauthorTae-Jin Song-
dc.contributor.googleauthorSang Won Han-
dc.contributor.googleauthorJoong Hyun Park-
dc.contributor.googleauthorJinkwon Kim-
dc.contributor.googleauthorYo Han Jung-
dc.contributor.googleauthorHan-Jin Cho-
dc.contributor.googleauthorSeong Hwan Ahn-
dc.contributor.googleauthorSung Ik Lee-
dc.contributor.googleauthorKwon-Duk Seo-
dc.contributor.googleauthorHyo Suk Nam-
dc.identifier.doi10.3390/jcm9030717-
dc.contributor.localIdA00410-
dc.contributor.localIdA00498-
dc.contributor.localIdA00702-
dc.contributor.localIdA01012-
dc.contributor.localIdA01142-
dc.contributor.localIdA01273-
dc.contributor.localIdA05600-
dc.contributor.localIdA02513-
dc.contributor.localIdA02648-
dc.contributor.localIdA03312-
dc.contributor.localIdA04369-
dc.relation.journalcodeJ03556-
dc.identifier.eissn2077-0383-
dc.identifier.pmid32155841-
dc.subject.keywordischemic stroke-
dc.subject.keywordoutcome-
dc.subject.keywordreperfusion-
dc.subject.keywordtherapy-
dc.contributor.alternativeNameKim, Dong Joon-
dc.contributor.affiliatedAuthor김동준-
dc.contributor.affiliatedAuthor김병문-
dc.contributor.affiliatedAuthor김영대-
dc.contributor.affiliatedAuthor김진권-
dc.contributor.affiliatedAuthor김현창-
dc.contributor.affiliatedAuthor남효석-
dc.contributor.affiliatedAuthor박형종-
dc.contributor.affiliatedAuthor유준상-
dc.contributor.affiliatedAuthor이경열-
dc.contributor.affiliatedAuthor이혜선-
dc.contributor.affiliatedAuthor허지회-
dc.citation.volume9-
dc.citation.number3-
dc.citation.startPage717-
dc.identifier.bibliographicCitationJOURNAL OF CLINICAL MEDICINE, Vol.9(3) : 717, 2020-03-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Preventive Medicine (예방의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers

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