Cone-beam computerized tomography (CBCT) can show an uncommon mandibular incisive canal that cannot be detected by panoramic radiography, which is used preoperatively to form the initial plan of the size and length of an implant fixture for surgical placement in the mandibular interforaminal area. Determination of the position and anatomical configuration of the mandibular incisive canal is challenging. The purpose of this case report is to discuss anatomical variations in the mandibular incisive canal and the mental canal by reviewing previous studies. Furthermore, we propose that the anterior loop length of the mental canal near the mental foramen, as well as the diameter of the mandibular incisive canal, should be verified by CBCT prior to performing implant surgery in the anterior mandibular area to prevent possible nerve damage.