Cited 8 times in
Body Fat Change and 8-year Incidence of Hypertension: Korean Genome and Epidemiology Study
DC Field | Value | Language |
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dc.contributor.author | 권유진 | - |
dc.contributor.author | 정동혁 | - |
dc.contributor.author | 조아라 | - |
dc.contributor.author | 이성범 | - |
dc.date.accessioned | 2020-06-04T08:40:38Z | - |
dc.date.available | 2020-06-04T08:40:38Z | - |
dc.date.issued | 2019-12 | - |
dc.identifier.issn | 1524-6175 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/175841 | - |
dc.description.abstract | Hypertension is strongly correlated with an increased risk of cardiovascular events. Recent studies have demonstrated that body fat percentage (BF%) is associated with cardiometabolic risk factors. The aim of this study was to investigate the association between a change in BF% and body mass index (BMI) and the incidence of new-onset hypertension in a normotensive Korean cohort. At baseline (2001-2002), 8848 participants aged 40-70 years were recruited for the study; follow-up surveys were completed in the year 2012. A total of 3902 adults (1866 men and 2036 women) were included in the final analysis. These subjects were divided into quartile groups according to changes in BF% and were followed for 8.4 years to monitor for the development of hypertension. A Poisson regression model was used to evaluate the relative risk (RR) for hypertension according to BF% change quartile. Additionally, we also stratified participants into four groups according to BMI change levels and body fat change levels. Finally, we compared two factors, BF% change, and BMI change, to determine which is more predictive of incident hypertension. In an adjusted model, compared with the lowest BF% quartile group, the risk of new-onset hypertension significantly increased with BF% change: Changes in risk were 0%-2.0% for quartile 3 subjects (RR: 1.32 [1.06-1.63]) and 2.0%-8.9% for quartile 4 participants (RR: 1.78 [1.43-2.19]). We also revealed that the RR for new-onset hypertension was 1.81 (95% CI: 1.47-2.21) for quartile 4 group subjects, compared with subjects in quartile 1 (change in BMI -6.80 to -0.86% [kg/m2 ]). Body fat gain and BMI increase were predictors of hypertension in this community-based Korean cohort. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Wiley Periodicals Inc. | - |
dc.relation.isPartOf | JOURNAL OF CLINICAL HYPERTENSION | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Body Fat Change and 8-year Incidence of Hypertension: Korean Genome and Epidemiology Study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Family Medicine (가정의학교실) | - |
dc.contributor.googleauthor | Sung-Bum Lee | - |
dc.contributor.googleauthor | A-Ra Cho | - |
dc.contributor.googleauthor | Yu-Jin Kwon | - |
dc.contributor.googleauthor | Dong-Hyuk Jung | - |
dc.identifier.doi | 10.1111/jch.13723 | - |
dc.contributor.localId | A04882 | - |
dc.contributor.localId | A03595 | - |
dc.contributor.localId | A05183 | - |
dc.relation.journalcode | J01320 | - |
dc.identifier.eissn | 1751-7176 | - |
dc.identifier.pmid | 31661604 | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/full/10.1111/jch.13723 | - |
dc.subject.keyword | body mass index | - |
dc.subject.keyword | fat percentage | - |
dc.subject.keyword | hypertension | - |
dc.subject.keyword | retrospective study | - |
dc.contributor.alternativeName | Kwon, Yu-Jin | - |
dc.contributor.affiliatedAuthor | 권유진 | - |
dc.contributor.affiliatedAuthor | 정동혁 | - |
dc.contributor.affiliatedAuthor | 조아라 | - |
dc.citation.volume | 21 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 1849 | - |
dc.citation.endPage | 1857 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CLINICAL HYPERTENSION, Vol.21(12) : 1849-1857, 2019-12 | - |
dc.identifier.rimsid | 64749 | - |
dc.type.rims | ART | - |
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