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Body Fat Change and 8-year Incidence of Hypertension: Korean Genome and Epidemiology Study

DC FieldValueLanguage
dc.contributor.author권유진-
dc.contributor.author정동혁-
dc.contributor.author조아라-
dc.contributor.author이성범-
dc.date.accessioned2020-06-04T08:40:38Z-
dc.date.available2020-06-04T08:40:38Z-
dc.date.issued2019-12-
dc.identifier.issn1524-6175-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/175841-
dc.description.abstractHypertension is strongly correlated with an increased risk of cardiovascular events. Recent studies have demonstrated that body fat percentage (BF%) is associated with cardiometabolic risk factors. The aim of this study was to investigate the association between a change in BF% and body mass index (BMI) and the incidence of new-onset hypertension in a normotensive Korean cohort. At baseline (2001-2002), 8848 participants aged 40-70 years were recruited for the study; follow-up surveys were completed in the year 2012. A total of 3902 adults (1866 men and 2036 women) were included in the final analysis. These subjects were divided into quartile groups according to changes in BF% and were followed for 8.4 years to monitor for the development of hypertension. A Poisson regression model was used to evaluate the relative risk (RR) for hypertension according to BF% change quartile. Additionally, we also stratified participants into four groups according to BMI change levels and body fat change levels. Finally, we compared two factors, BF% change, and BMI change, to determine which is more predictive of incident hypertension. In an adjusted model, compared with the lowest BF% quartile group, the risk of new-onset hypertension significantly increased with BF% change: Changes in risk were 0%-2.0% for quartile 3 subjects (RR: 1.32 [1.06-1.63]) and 2.0%-8.9% for quartile 4 participants (RR: 1.78 [1.43-2.19]). We also revealed that the RR for new-onset hypertension was 1.81 (95% CI: 1.47-2.21) for quartile 4 group subjects, compared with subjects in quartile 1 (change in BMI -6.80 to -0.86% [kg/m2 ]). Body fat gain and BMI increase were predictors of hypertension in this community-based Korean cohort.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherWiley Periodicals Inc.-
dc.relation.isPartOfJOURNAL OF CLINICAL HYPERTENSION-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleBody Fat Change and 8-year Incidence of Hypertension: Korean Genome and Epidemiology Study-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Family Medicine (가정의학교실)-
dc.contributor.googleauthorSung-Bum Lee-
dc.contributor.googleauthorA-Ra Cho-
dc.contributor.googleauthorYu-Jin Kwon-
dc.contributor.googleauthorDong-Hyuk Jung-
dc.identifier.doi10.1111/jch.13723-
dc.contributor.localIdA04882-
dc.contributor.localIdA03595-
dc.contributor.localIdA03595-
dc.contributor.localIdA05183-
dc.contributor.localIdA05183-
dc.relation.journalcodeJ01320-
dc.identifier.eissn1751-7176-
dc.identifier.pmid31661604-
dc.identifier.urlhttps://onlinelibrary.wiley.com/doi/full/10.1111/jch.13723-
dc.subject.keywordbody mass index-
dc.subject.keywordfat percentage-
dc.subject.keywordhypertension-
dc.subject.keywordretrospective study-
dc.contributor.alternativeNameKwon, Yu-Jin-
dc.contributor.affiliatedAuthor권유진-
dc.contributor.affiliatedAuthor정동혁-
dc.contributor.affiliatedAuthor정동혁-
dc.contributor.affiliatedAuthor조아라-
dc.contributor.affiliatedAuthor조아라-
dc.citation.volume21-
dc.citation.number12-
dc.citation.startPage1849-
dc.citation.endPage1857-
dc.identifier.bibliographicCitationJOURNAL OF CLINICAL HYPERTENSION, Vol.21(12) : 1849-1857, 2019-12-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Family Medicine (가정의학교실) > 1. Journal Papers

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