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Self-reported insomnia as a marker for anxiety and depression among migraineurs: a population-based cross-sectional study

 Kyung Min Kim  ;  Dong Hyun Lee  ;  Eun Ju Lee  ;  Yun Ho Roh  ;  Won-Joo Kim  ;  Soo-Jin Cho  ;  Kwang Ik Yang  ;  Chang-Ho Yun  ;  Min Kyung Chu 
 SCIENTIFIC REPORTS, Vol.9(1) : 19608, 2019 
Journal Title
Issue Date
Anxiety, depression, and insomnia are highly prevalent among migraineurs and are associated with negative health consequences. Anxiety and depression, however, unlike insomnia, are usually underdiagnosed, due to less self-reporting of these two conditions. The aim of the present study was to evaluate the risk of anxiety and depression in migraineurs with self-reported insomnia, using a general population-based sample. We used data from a nationwide population-based survey on headache and sleep, the Korean Headache-Sleep Study. Of all 2,695 participants, 143 (5.3%), 268 (10.0%), 116 (4.3%), and 290 (10.8%) were classified as having migraine, anxiety, depression, and self-reported insomnia, respectively. The risk of anxiety (odds ratio [OR] = 7.0, 95% confidence interval [CI] = 3.0-16.7) and depression (OR = 3.3, 95% CI = 1.3-8.5) was significantly increased in migraineurs with self-reported insomnia. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) for anxiety in migraineurs with self-reported insomnia were 46.5%, 89.0%, 64.5%, and 79.5%, respectively. For depression, the sensitivity, specificity, PPV, and NPV were 41.7%, 82.4%, 32.3%, and 87.5%, respectively. Self-reported insomnia is likely to be comorbid with anxiety and depression in migraineurs and could thus be a useful predictor of anxiety and depression in migraine.
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Kyung Min(김경민) ORCID logo https://orcid.org/0000-0002-0261-1687
Kim, Won Joo(김원주) ORCID logo https://orcid.org/0000-0002-5850-010X
Lee, Dong Hyun(이동현)
Chu, Min Kyung(주민경) ORCID logo https://orcid.org/0000-0001-6221-1346
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